Abstract

During the 1960s at Rotta Research Laboratorium, Rovati [1] developed a gastrin receptor antagonist named proglumide, i.e., DL-4-benzamido-N, N-dipropyl-glutaramic acid. Proglumide has been used for several years for the treatment of peptic ulcer.

Keywords

HPLC Amide Pancreatitis Amylase Methoxy 

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References

  1. 1.
    Rovati AL (1968) The relationship between chemical structure of a new dicarboxylic amino-acid derivative and antigastrin activity in the rat. Br J Pharmacol 34:677–682Google Scholar
  2. 2.
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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • L. C. Rovati
    • 1
  1. 1.Department of Clinical PharmacologyRotta Research LaboratoriumMonza (Milano)Italy

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