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Interaktionen von Röntgenkontrastmitteln mit der Gefäßwand

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Röntgenkontrastmittel

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Zusammenfassung

Die Entwicklung der Raster- und Fluoreszenzelektronenmikroskopie hat neue morphologische Erkenntnisse über den Aufbau der Intima, speziell des Endothels vermittelt [30, 44]. Neue histo- und immunhistochemische Methoden, Untersuchungen an endothelialen Zellkulturen in vitro und in vivo sowie Studien an isoliert perfundierten Organen haben darüber hinaus zeigen können, daß die Endothelzelle zu funktionellen Leistungen befähigt ist.

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Literatur

  1. Albrechtsson U, Olsson CG (1979) Thrombosis after phlebography: A comparison of two contrast media. Cardiovasc Radiol 2: 9–18

    Article  PubMed  CAS  Google Scholar 

  2. Almén T (1971) Toxicity of radiocontrast media. In: Knoefel PK (ed) Radiocontrast agents, vol 2. Pergamon, Oxford, pp 443 ff.

    Google Scholar 

  3. Armstrong D, Jepson JB, Keele CA, Stewart JW (1953) Observations on chemical excitants of cutaneous pain in man. J Physiol (Lond) 120: 326–351

    CAS  Google Scholar 

  4. Aspelin P, Teitel P, Almén T (1980) Effect of iohexol on red cell deformability in vitro. Acta Radiol [Suppl] (Stockh) 362: 127–130

    CAS  Google Scholar 

  5. Atkins P, Hawkins LA (1965) The diagnosis of deep vein thrombosis in the legs using 125 J-fibrinogen. Lancet II: 1217–1219

    Article  Google Scholar 

  6. Bettmann MA, Salzman EW, Rosenthal D et al. (1980) Reduction of venous thrombosis complicating phlebography. AJR 134: 1169–1172

    PubMed  CAS  Google Scholar 

  7. Brightman MW, Hori M, Rapoport SI, Reese TS, Westergaard E (1973) Osmotic opening of tight-junctions in cerebral endothelium. J Comp Neurol 152: 317–325

    Article  PubMed  CAS  Google Scholar 

  8. Brooks B (1924) Intraarterial injection of sodium iodid. JAMA 82: 1026

    Google Scholar 

  9. Christmann D, Wackenheim A (1982) Effects of contrast media on cell cultures. In: Amiel M (ed) Contrast media in radiology. Springer, Berlin Heidelberg New York Tokyo, pp 49–51

    Chapter  Google Scholar 

  10. Clementi F, Palade GE (1969) Intestinal capillaries. II. Structural effects of EDTA and histamine. J Cell Biol 42/II: 706–714

    Article  PubMed  CAS  Google Scholar 

  11. Ferreira SH, Moncada S, Vane JR (1973) Prostaglandins and the mechanism of analgesia produced by aspirin like drugs. Br J Pharmacol 49: 86–97

    PubMed  CAS  Google Scholar 

  12. Furchtgott RF (1983) Role of endothelium in the response of vascular smooth muscle. Circ Res 53/5: 557–573

    Google Scholar 

  13. Giang DW, Kido DK (1989) Transient global amnesia associated with cerebral angiography performed with use of iopamidol. Radiology 172: 195–196

    PubMed  CAS  Google Scholar 

  14. Golman K, Almén T (1984) Urographic contrast media and methods of investigative uroradiology. In: Sovak M (ed) Radiocontrast agents. Springer, Berlin Heidelberg New York Tokyo, pp 127–197

    Google Scholar 

  15. Golman K, Holtas S (1980) Proteinuria produced by urographic contrast media. Invest Radiol [Suppl] 15: 61–67

    Article  Google Scholar 

  16. Gonsette RE (1982) The neurotoxicity of water-soluble contrast media: actual concepts and future. In: Amiel M (ed) Contrast media in radiology, 1st European Workshop, Lyon 1981. Springer, Berlin Heidelberg New York Tokyo, pp 115–122

    Google Scholar 

  17. Gospos C, Freudenberg N, Elke M (1983) Wirkung von Röntgenkontrastmitteln auf das Endothel der V. cava der Ratte. ROFO 139/5: 553–555

    Article  PubMed  CAS  Google Scholar 

  18. Gospos C, Freudenberg N, Staubesand J, Mathias K, Papacaralampous X (1983) The effect of contrast media on the aortic endothelium of rats. Radiology 147: 685–688

    PubMed  CAS  Google Scholar 

  19. Gottlob R (1975) Untersuchungen an den obersten Klappen der Vena saphena magna bei Varizen. Zentralblatt Chir 100: 1306–1315

    CAS  Google Scholar 

  20. Gottlob R (1980) Lokale Kontrastmittelschäden — Ursachen, Testmethoden, Ergebnisse. Krankenhausarzt 53: 549–555

    Google Scholar 

  21. Gottlob R (1981) Die Auswertung endothelschädigender Wirkungen verschiedener angiographischer Kontrastmittel an einem Tiermodell. ROFO 135/5: 560–565

    Article  PubMed  CAS  Google Scholar 

  22. Grabowski EF (1989) Effects of contrast media on endothelial cell monolayers under controlled flow conditions. In: Enge J, Edgren J (eds) Patient safety and adverse events in contrast medium examinations. Excerpta Medica, Amsterdam, pp 85–95

    Google Scholar 

  23. Guzman F, Braun C, Lim RKS (1962) Visceral pain and the pseudoaffective response to intra-arterial injection of bradykinin and other algesic agents. Arch Int Pharmacodyn Ther 136:353–384

    PubMed  CAS  Google Scholar 

  24. Hagen B (1985) Die Objektivierung der Endothelverträglichkeit nicht-ionischer und ionischer Kontrastmittel mit dem Radio-Jod-Fibrinogentest bei der Beinphlebographie. In: Zeitler E (Hrsg) Klinische Pharmakologie der Kontrastmittel. Schnetztor, Konstanz, S 94–105

    Google Scholar 

  25. Hagen B, Clauss W (1982) Kontrastmittel und Schmerz bei der peripheren Arteriographie. Randomisierter, intraindividueller Doppelblindversuch: Ioglicinat, Ioglicinat-Lidocain, Ioxaglat. Radiologe 22:470–475

    PubMed  CAS  Google Scholar 

  26. Hagen B, Klink G (1983) Contrast media and pain. Hypotheses on the genesis of pain occurring on intraarterial administration of contrast media. In: Taenzer V, Zeitler E (eds) Contrast media. Thieme, Stuttgart, pp 50–56

    Google Scholar 

  27. Hagen B, Wenzel-Hora BI (1989) Initial experience with a non-ionic dimeric contrast medium (Iotrolan) in direct and indirect arteriography: A randomized, intraindividual double-blind study in 60 patients. In: Taenzer V, Wende S (eds) Recent developments in non-ionic contrast media. Thieme, Stuttgart, pp 54–60

    Google Scholar 

  28. Hagen B, Siefert HM, Mützel W, Speck U (1983) Increased pain reactions as hangover phenomena after intra-arterial injections of contrast media in rats. In: Taenzer V, Zeitler E (eds) Contrast media. Thieme, Stuttgart, pp 57–61

    Google Scholar 

  29. Hagen B, Nauert C, Juan H, Sametz W, Lienemann B, Mützel W (1989) Experimental evaluation of radiographic contrast media in perivascular pain receptors in the perfused isolated rabbit ear. In: Taenzer V, Wende S (eds) Recent developments in non-ionic contrast media. Thieme, New York, pp 46–53

    Google Scholar 

  30. Hammersen F (1977) Bau und Funktion der Blutkapillaren. In: Meessen H (Hrsg) Allgemeine Pathologie der Mikrozirkulation. Springer, Berlin Heidelberg New York (Handbuch der allgemeinen Pathologie, Bd III/7, S 135–230)

    Google Scholar 

  31. Hammersen F, Hammersen E (1985) Das Endothel — ein disseminiertes, metabolisch aktives Organ. In: Meßmer K (Hrsg) Angiodynamik und Angiopathie. Zuckschwerdt, München, S 15–32

    Google Scholar 

  32. Iggo A (1974) Pain receptors. In: Bonica JJ, Procacci P, Pagni CA (eds) Recent advances on pain. Thomas, Springfield/Ill, pp 3–35

    Google Scholar 

  33. Juan H, Lembeck F (1974) Action of peptides and other algesic agents on paravascular pain receptors of the isolated perfused rabbit ear. Naunyn Schmiedebergs Arch Pharmacol 283:151–164

    Article  PubMed  CAS  Google Scholar 

  34. Juan H, Lembeck F (1976) Release of prostaglandins from the isolated perfused rabbit ear by bradykinin and acetylcholine. Agents Actions 6: 642–645

    Article  PubMed  CAS  Google Scholar 

  35. Junck L, Marshall WH (1983) Neurotoxicity of radiological contrast agents. Ann Neurol 13:469–484

    Article  PubMed  CAS  Google Scholar 

  36. Katayama H, Kozerka T, Takashima T, Matsuura K, Yamaguchi K (1988) Adverse reactions to contrast media: Ionic CM versus non-ionic CM. The Japanese Committee on Safety of Contrast Media. Nippon Acta Radiol 48: 214–216

    PubMed  CAS  Google Scholar 

  37. Karino T, Motomyia M (1982) Flow pattern in the pocket of various valves and their implication in thrombogenesis (Abstract). Int Symp on venous diseases of the lower limbs, 10.–12. März, Florenz

    Google Scholar 

  38. Kormano MJ (1981) Kinetics of contrast media after bolus injection and infusion. In: Felix R, Kazner E, Wegener DH (eds) Contrast media in computed tomography. Excerpta Medica, Amsterdam, pp 38–45

    Google Scholar 

  39. Laerum F (1987) Cytotoxic effects of six angiographic contrast media on human endothelium in culture. Acta Radiol 28/1:99–105

    Article  PubMed  CAS  Google Scholar 

  40. Laerum F, Dehner LP, Rysavy J, Amplatz K (1987) Double blind evaluation of the effects of various contrast media on extremity veins in the dog. Acta Radiol 28/1: 107–113

    Article  PubMed  CAS  Google Scholar 

  41. Lasser EC (1984) Adverse systemic reactions to contrast media. In: Sovak M (ed) Radiocontrast agents. Springer, Berlin Heidelberg New York (Handbook of experimental pharmacology, vol 73, pp 525–533)

    Google Scholar 

  42. Lim RKS (1970) Pain. Ann Rev Physiol 32: 269–288

    Article  CAS  Google Scholar 

  43. Ljungner H, Bergquist D (1983) Decreased fibrinolytic activity in the bottom of human vein valve pockets. VASA 12: 333–336

    PubMed  CAS  Google Scholar 

  44. Majno G, Joris I (1978) Endothelium 1977: A review. Adv Exp Med Biol 104: 169–225

    PubMed  CAS  Google Scholar 

  45. May R, Mignon G (1978) Thrombophlebitis nach Phlebographie. In: Frommhold W, Hacker H, Schmitt HE, Vogelsang H (Hrsg) Amipaque Workshop, Berlin, 1978. Excerpta Medica, Amsterdam, p 214–221

    Google Scholar 

  46. May R, Nissl R (1969) Gefäßverschlüsse nach Angiographien. ROFO 110: 64–71

    Article  CAS  Google Scholar 

  47. Merker H-J (1982) Mikrozirkulation. 2. Funktionelle Aspekte der Mikrozirkulation. Schriftenreihe Deutsche Abbott GmbH, Wiesbaden, S 1–21

    Google Scholar 

  48. Moncada S, Ferreira SH, Vane JR (1978) Pain and inflammatory mediators. Springer, Berlin Heidelberg New York

    Google Scholar 

  49. Moore RM, Moore RE (1933) Studies on the pain-sensibility of arteries, I + II. Am J Physiol 104/2: 259–275

    Google Scholar 

  50. Morgan ML, Bettmann M (1989) Effects of X-ray contrast media and radiation on human vascular endothelial cells in vitro. Cardiovasc Intervent Radiol 12: 154–160

    Article  PubMed  CAS  Google Scholar 

  51. Mützel W (1981) Properties of conventional contrast media. In: Felix R, Kazner E, Wegener OH (eds) Contrast media in computed tomography. Int Workshop, Berlin 1981, pp 19–26

    Google Scholar 

  52. Negus D, Pinto DJ, Le Quense LP, Brown N, Chapman M (1968) 125-J-labelled fibrinogen in the diagnosis of deep vein thrombosis and its correlation with phlebography. Br J Surg 55: 835–839

    Article  PubMed  CAS  Google Scholar 

  53. Nyman U, Almén T (1980) Effects of contrast media on aortic endothelium. Experiments in the rat with non ionic and ionic monomeric and monoacidic dimeric contrast media. Acta Radiol [Suppl] (Stockh) 362: 65–71

    CAS  Google Scholar 

  54. Odermatt W (1922) Sensitivity of blood vessels. Brunn’s Beiträge Klin Chir 127: 1

    Google Scholar 

  55. Paajanen H, Uotila P, Kormano M (1983) Different effect of diatrizoate and iopamidol on prostaglandin synthesis in perfused hamster-lungs. Invest Radiol 18: 375–381

    Article  PubMed  CAS  Google Scholar 

  56. Parvez Z, Marsan RE, Moncada R, Patel N (1988) Effect of contrast media on prostaglandin synthesis in vivo. Invest Radiol [Suppl] 23: 178–181

    Google Scholar 

  57. Pearson JD (1983) Stoffwechselleistungen endothelialer Zellen. In: Meßmer K, Hammersen F (Hrsg) Struktur und Funktion endothelialer Zellen. Basel, S 126–139

    Google Scholar 

  58. Raininko R (1979) Endothelial permeability increase produced by angiographic media. ROFO 131/4: 433–438

    Article  PubMed  CAS  Google Scholar 

  59. Raininko R (1984) Immediate effect of meglumine diatrizoate on the vascular endothelium. Eur J Radiol 4: 14–18

    PubMed  CAS  Google Scholar 

  60. Rapoport SJ, Levitan H (1974) Neurotoxicity of x-ray contrast media — Relation to lipid solubility and blood-brain-barrier permeability. AJR 123: 186–193

    Google Scholar 

  61. Reese TS, Karnovsky MJ (1967) Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol 34:207–217

    Article  PubMed  CAS  Google Scholar 

  62. Reimers HJ, Misera R (1981) Prostaglandinstoffwechsel und Thrombogenese. In: Breddin K, Gross D, Rotter W (Hrsg) Thrombosemodelle am Tier. 15. Angiol Sympos Kitzbühel. Schattauer, Stuttgart, S 217–229

    Google Scholar 

  63. Rose B, Simpson I, Loewenstein WR (1977) Calcium ion produces graded changes in permeability of membrane channels in cell junction. Nature 267: 625

    Article  PubMed  CAS  Google Scholar 

  64. Scherberich J, Tuengerthal S, Kollath J (1983) Monitoring of contrast media nephrotoxicity by specific kidney tissue proteinuria of membrane antigens. In: Taenzer V, Zeitler E (eds) Contrast media. Thieme, Stuttgart, S 37–42

    Google Scholar 

  65. Schmitt HE, Widmer LK (1984) Phlebographie mit niederosmolaren Kontrastmitteln. Vasa 13/1:32–35

    PubMed  CAS  Google Scholar 

  66. Sicuteri F, Fanciulacci M, Franchi G, Del Bianco PL (1965) Serotonin-bradykinin potentiation on the pain receptor in man. Life Sci 4: 309–316

    Article  PubMed  CAS  Google Scholar 

  67. Sovak M, Ranganathan R, Lang JH, Lasser EC (1978) Concepts in design of improved intravascular contrast agents. Ann Radiol 21: 283–289

    PubMed  CAS  Google Scholar 

  68. Speck U, Siefert HM, Klink G (1980) Contrast media and pain in peripheral arteriography. Invest Radiol 15: 335–389

    Article  Google Scholar 

  69. Speck U, Press WR, Mützel W (1983) Albuminuria following renal arteriography with various ionic and non-ionic contrast agents in the rat. In: Taenzer V, Zeitler E (eds) Contrast media. Thieme, Stuttgart, pp 25–29

    Google Scholar 

  70. Sterrett PR, Bradley IM, Kitten GT, Janssen HF, Holloway LS (1976) Cerebrovasculature permeability changes following experimental cerebral angiography. A light and electron microscopic study. J Neurol Sci 30: 385–403

    Article  PubMed  CAS  Google Scholar 

  71. Stöhr P jr (1950) Acta Neuroveg (Wien) 1: 74

    Article  Google Scholar 

  72. Swanson DP, Thrall JH, Shetty PC (1986) Evaluation of intravascular low-osmolality contrast agents. Clin Pharm 5: 877–891

    PubMed  CAS  Google Scholar 

  73. Ultravist-Produktinformation (1985). Schering, Berlin

    Google Scholar 

  74. Van Andel GJ (1980) Arterial occlusion following angiography. Br J Radiol 53: 747–753

    Article  PubMed  Google Scholar 

  75. Violante MR, Thomsen KR, Fischer HW, Kenyon T (1978) Ventricular fibrillation from diatrizoate with and without chelating agents. Radiology 128: 497

    PubMed  CAS  Google Scholar 

  76. Waldron RL, Bridenbaugh RB, Dempsey EW (1974) Effect of angiographic contrast media at the cellular level in the brain — hypertonic vs. chemical action. AJR 122: 469–476

    Google Scholar 

  77. Whitehouse WM, Queral LA, Flinn WR, Kwaan HC, Bergan SJ, Yao JST (1981) The effect of sodium diatrizoate on the fibrinolytic activity of saphenous vein intima. J Surg Res 30: 391–397

    Article  PubMed  Google Scholar 

  78. Zinner G, Gottlob R (1959) Die gefäßschädigende Wirkung verschiedener Röntgenkontrastmittel, vergleichende Untersuchungen. ROFO 91: 507

    Article  CAS  Google Scholar 

  79. Zottermann Y (1959) The peripheral nervous mechanism of pain — a brief review. In: Ciba Foundation study group Nr. 1. Pain and itch. Nervous mechanisms. Churchill, London, pp 13–34

    Google Scholar 

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  1. B. Hagen
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Editors and Affiliations

  1. Institut für Klinische Radiologie, Westfälische Wilhelms-Universität, Albert-Schweitzer-Straße 33, W-4400, Münster, Bundesrepublik Deutschland

    P. E. Peters

  2. Radiologisches Zentrum, Klinikum Nürnberg, Flurstraße 17, W-8500, Nürnberg, Bundesrepublik Deutschland

    E. Zeitler

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Hagen, B. (1991). Interaktionen von Röntgenkontrastmitteln mit der Gefäßwand. In: Peters, P.E., Zeitler, E. (eds) Röntgenkontrastmittel. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76338-0_4

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  • DOI: https://doi.org/10.1007/978-3-642-76338-0_4

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