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Anaphylaktoide Reaktionen durch Röntgenkontrastmittel

  • D. Vieluf
  • J. Ring
Conference paper

Zusammenfassung

Unter einer arzneimittelbedingten Unverträglichkeitsreaktion versteht man eine unerwünschte, nicht erwartete Reaktion bei einer klinisch üblichen Dosierung eines Medikamentes. Dabei können unterschiedliche Mechanismen zu klinisch relevanten Unverträglichkeitsreaktionen führen. Entspricht die Symptomatik einer solchen Unverträglichkeitsreaktion dem pharmakologischen Effekt eines Medikamentes, so handelt es sich um eine Intoleranzreaktion, d. h. eine verstärkte individuelle Empfindlichkeit des Patienten im Sinne des erwarteten pharmakologischen bzw. toxischen Effekts. Zeigt sich hingegen eine Überempfindlichkeitsreaktion, die nicht durch die pharmakologische Toxizität des Auslösers zu erklären ist, so kann diese auf einer spezifischen immunologischen Sensibilisierung beruhen (allergische Reaktion) oder nicht-immunologisch ausgelöst sein (pseudo-allergische Reaktion bei Symptomen, die einer allergischen Reaktion weitgehend gleichen) [18, 35, 58, 61, 64, 65, 67–69, 81, 98].

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  • D. Vieluf
  • J. Ring

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