Hereafter we shall be concerned with diploid populations. We begin by investigating in this chapter the genetic structure of a randomly mating population in the absence of selection, mutation, and random drift. This part of population genetics was the first to be understood, and a thorough grasp of its principles is required for the formulation and interpretation of most evolutionary models. To ensure the desired comprehension, some fairly detailed examples and problems, of a type that has proved useful in human genetics, are presented. In Sect. 3.1 we shall derive the Hardy-Weinberg Law. We shall proceed to sex-linkage and two loci in Sects. 3.2 and 3.3 and discuss the effect of population subdivision in Sect. 3.4. In Sect. 3.5 we investigate deviations from the Hardy-Weinberg Law in a finite population.
KeywordsGenotypic Frequency Random Mating Finite Population Linkage Equilibrium Panmictic Population
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