Zusammenfassung
Extraintestinale Erkrankungen durch Escherichia coli, der zahlenmäßig bedeutendsten Spezies der aerob wachsenden Darmflora des Menschen, sind häufig und betreffen fast alle Organsysteme: Harnweginfektionen, Pneumonie, Osteomyelitis und septische oder meningitische Komplikationen bei abwehrgeschwächten Patienten oder Neugeborenen. E. coli spielen aber auch an ihrem natürlichen Standort eine bedeutende Rolle als Erreger von Durchfallerkrankungen.
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Literatur
Barrett TJ, Potter ME, Wachsmuth IK (1989) Continuous peritoneal infusion of Shiga-like toxin II (SLTII) as a model for SLT II-induced diseases. J Infect Dis 159: 774–777
Bettelheim KA, Dwyer BW, Goldwater PN, Bourne AJ (1989) Toxigenic Escherichia coli associated with sudden infant death syndrome. Med J Austr 151: 538
Bitzan M, Karch H, Altrogge H, Strehlau J, Bläker F (1988) Hemolytic-uremic syndrome associated with a variant Shiga-like cytotoxin of Escherichia coli 0111. Pediatr Infect Dis J 7: 128–132
Bitzan M, Karch H, Heesemann J (1988) Verotoxinproduzierende Escherichia coli bei Enteritiden und dem hämolytisch-urämischen Syndrom (HUS). Kassenarzt 30: 31–33
Bitzan M, Karch H, Maas MG, Meyer T, Rüssmann H, Aleksic S, Bockemühl J (1990) Clinical and genetic aspects of Shiga-like toxin in traditional enteropathogenic Escherichia coli. Zentralbl Bakt Hyg A (im Druck)
Byrnes JJ, Moake JL (1986) Thrombotic thrombocytopenic purpura and the haemolytic-uraemic syndrome: Evolving concepts of pathogenesis and therapy. Clin Haematol 15: 413–442
Carter ASO, Borczyk AA, Carlson JAK, Harvey B, Hockin JC, Karmali MA, Krishnan C, Korn C, Lior H (1987) A severe outbreak of Escherichia coli 0157: H7-associated hemor-rhagic colitis in a nursing home. N Engl J Med 317: 1496–1600
Crosse BA (1990) Haemolytic-uraemic syndrome in adults. Lancet 335: 1526–1528 (letter)
Dorn CR, Scotland SM, Smith HR, Willshaw GA, Rowe B (1989) Properties of vero cytotoxin-producing Escherichia coli of human and animal origin belonging to serotypes other than 0157: H7. Epid Inf 103: 83–95
Ewing W (1986) Identification of enterobacteriaceae. 4th edn. Elsevier, New York
Fong JSC, Chadarevian J-P de, Kaplan BS (1982) Hemolytic-uremic syndrome. Current concepts and management. Pediatr Clin North Am 29/4: 835–856
Gasser C, Gautier E, Steck A, Siebenmann RE, Oechslin R (1955) Hämolytisch-urämische Syndrome: Bilaterale Nierenrindennekrosen bei akuten erworbenen hämolytischen An-ämien. Schweiz Med Wochenschr 85: 905–909
Gransden WR, Damm MAS, Anderson JD, Carter JE, Lior H (1985) Haemorrhagic colitis and balanitis associated with verotoxin-producing Escherichia coli 0157: H7. Lancet 11: 150 (letter)
Griffin PM, Ostroff SM, Tauxe RV, Greene KD, Wells JG, Lewis JH, Blake PA (1988) Illnesses associated with Escherichia coli 0157: H7 infections. A broad clinical spectrum. Ann Intern Med 109: 705–712
Gyles CL, DeGrandis SA, MacKenzie C, Brunton JL (1988) Cloning and nucleotide sequence analysis of the genes determining Verocytotoxin production in a porcine edemea disease isolate of Escherichia coli. Microbiol Pathogen 5: 419–426
Ito H, Terai A, Kurazono H, Takeda Y, Nishibuchi M (1990) Cloning and nucleotide sequencing of Vero toxin 2 variant genes from Escherichia coli 091: H21 isolated from a patient with the hemolytic uremic syndrome. Microbiol Pathogen 8: 47–60
Jackson MP, Neill RJ, O’Brien AD, Holmes RK, Newland JW (1987) Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages from Escherichia coli 933. FEMS Microbiol Lettr 44: 109–114
Karch H (1988) Pathogenese, Epidemiologie und Diagnostik enterohämorrhagischer Esche-richia coli. Habilitationsschrift, Universität Hamburg
Karch H, Bitzan M, Pietsch R, Stenger K-O, Wulffen H von, Heesemann J, Düsing R (1988) Purified verotoxins of Escherichia coli 0157: H 7 decrease prostacyclin synthesis by endothelial cells. Microbiol Pathogen 5: 215–221
Karch H, Heesemann J, Laufs R (1987) Phageassociated cytotoxin production by and enteroadhesiveness of enteropathogenic escherichia coli isolated from infants with diarrhea in West Germany. J Infect Dis 155: 707–715
Karch H, Heesemann J, Laufs R, O’Brien AD, Tacket CO, Levine MM (1987) A plasmid of enterohemorrhagic Escherichia coli 0157: H7 is required for expression of a new fimbrial antigen and for adhesion to epithelial cells. Infect Immun 55: 455–461
Karch H, Meyer T (1989) Single primer pair for amplifying segments of distinct Shiga-like-toxin genes by polymerase chain reaction. J Clin Microbiol 27(12): 1751–2757
Karch H, Meyer T (1989) Evaluation of oligonucleotide probes for identification of Shiga-like-toxin-producing Escherichia coli. J Clin Microbiol 27: 1180–1186
Karch H, Rüssmann H, Meyer T, Bitzan M, Heesemann J (1989) Enterohämorrhagische Escherichia coli und Yersinien bei chronisch-entzündlichen Darmerkrankungen. In: Müller J, Ottenjann R, Seifert J (Hrsg) Ökosystem Darm. Morphologie, Mikrobiologie, Immuno-logie. Springer, Berlin Heidelberg New York Tokyo, S 101–116
Karch H, Strockbine NA, O’Brien AD (1986) Growth of Escherichia coli in the presence of trimethoprim-sulfamethoxazole facilitates detection of Shiga-like toxin producing strains by colony blot assay. FEMS Microbiol Lett 35: 141–145
Karch H, Wiß R, Gloning H, Emmrich P, Aleksic S, Bockemühl J (1990) Hämolytisch-urämisches Syndrom bei Kleinkindern durch Verotoxin-produzierende Escherichia coli. Dtsch Med Wochenschr 115: 489–495
Karmali MA (1989) Infection by verocytotoxin-producing Escherichia coli. Clin Microbiol Rev 2: 15–38
Karmali MA, Petrie M, Lim C, Fleming PC, Arbus GS, Lior H (1985) The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Esche-richia coli. J Infect Dis 151: 775–781
Karmali MA, Steele BT, Petrie M, Lim C (1983) Sporadic cases of haemolytic-uraemic syndrome associated with faecal cytotoxin and cytotoxin-producing Escherichia coli in stools. Lancet 1: 619–620
Klemt M, Bitzan M (1989) Shiga-like toxin neutralizing antibodies in children with hemolytic uremic syndrome and in healthy controls. Zentralbl Bakt Hyg A (Abstract)
Kollaritsch H (1989) Wirksamkeit von Saccharomyces cerevisiae Hansen CBS 5926 in der Prophylaxe der Reisediarrhö: Ergebnisse einer Doppelblindstudie. In: Müller J, Ottenjann R, Seifert J (Hrsg) Ökosystem Darm. Morphologie, Mikrobiologie, Immunologie. Springer, Berlin Heidelberg New York Tokyo, S 80–87
Koster F, Levin J, Walker L, Tung KSK, Gilman RH, Rahaman MM, Majid MA, Islam S, Williams RCJ (1978) Hemolytic-uremic syndrome after shigellosis. Relation to endotoxemia and circulating immune complexes. N Engl J Med 298: 927–933
Levine MM, Nataro JP, Karch H, Baldini MM, Kaper JB, Black RE, Clements ML, O’Brien AD (1985) The diarrheal response of humans to some classic serotypes of enteropathogenic Escherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor. J Infect Dis 152: 550–559
Levine MM (1987) Escherichia coli that cause diarrhea: Enterotoxinogenic, enteropatho-genic, enteroinvasive, enterohemorrhagic, and enteroadherent. J Inf Dis 155: 377–389
Levine MM, Prado V, Robins-Browne R, Lior H, Kaper JB, Moseley SL, Giquelais K, Nataro JP, Vial P, Tall B (1988) Use of DNA probes and HEp-2 cell adherence assay to detect diarrheagenic Escherichia coli. J Infect Dis 158: 224–228
Levine MM, Xu J-G, Kaper JB, Lior H, Prado V, Tall B, Nataro J, Karch H, Wachsmuth IK (1987) A DNA probe to identify enterohemorrhagic Escherichia coli of 0157:Ή7 and other serotypes that cause hemorrhagic colitis and hemolytic uremic syndrome. J Infect Dis 156: 175–182
Lingwood CA, Law H, Richardson S, Petrie M, Brunton JL, De Grandis S, Karmali M (1987) Glycolipid binding of purified and recombinant Escherichia coli produced verotoxin in vitro. J Biol Chem 262: 8834–8839
Meyer T, Bitzan M, Sandkamp O, Karch H (1989) Synthetic oligodeoxyribonucleotide probes to detect verocytotoxin-producing Escherichia coli in diseased pigs. FEMS Microbiol Lett 57: 247–252
Moake JL, Byrnes JJ, Troll JH, Rudy CK, Weinstein MJ, Culannino NM, Hong SL (1984) Abnormal factor VIII: von Willebrand factor patterns in the plasma of patients with the hemolytic uremic syndrome. Blood 64: 592–598
Morrison DM, Tyrell DLJ, Jewell LD (1986) Colonic biopsy in verotoxin-induced hemorrha-gic colitis and thrombotic thrombocytopenic purpura (TTP). Am J Clin Pathol 86: 108–112
Neill MAAJ, Rosen H (1985) Hemorrhagic colitis with Escherichia coli 0157: H7 preceding adult hemolytic uremic syndrome. Arch Intern Med 145: 2215–2217
Notenboom RH, Borczyk A, Karmali MA, Duncan LMC (1987) Clinical relevance of a serological cross-reaction between Escherichia coli 0157 and Brucella abortus. Lancet 11: 745 (letter)
O’Brien AD, Holmes RK (1987) Shiga and Shiga-like toxins. Microbiol Rev 51: 206–220
Örskov F, Örskov I (1984) Serotyping of Escherichia coli. In: Bergan T (ed) Methods in microbiology, Vol 14. Academic Press, London, pp 43–112
Padhye W, Beery JT, Kitteil FB, Doyle MP (1987) Colonic hemorrhage produced in mice by a unique Vero cell cytotoxin from an Escherichia coli strain that causes hemorrhagic colitis. J Infect Dis 155: 1249–1253
Pai CH, Kelly JK, Meyers GL (1986) Experimental infection of infant rabbits with Verotoxin-producing Escherichia coli. Infect Immun 51: 16–23
Pavia AT, Nichols CR, Green DP et al. (1990) Hemolytic-uremic syndrome during an outbreak of Escherichia coli 0157: H7 infections in institutions for mentally retarded persons: clinical and epidemiologic observations. J Pediatr 116: 544–551
Proesmans W, Eeckels R (1989) The hemolytic uremic syndromes. Adv Intern Med Pediatr 58: 55–82
Reisbig R, Olsnes S, Eiklid K (1981) The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60S ribosomal subunit. J Biol Chem 256: 8739–8744
Remuzzi G (1987) HUS and TTP: variable expression of a single entity. Kidney Int 32: 292–308
Riley LW (1987) The epidemiologic, clinical, and microbiologic features of hemorrhagic colitis. Ann Rev Microbiol 41: 383–407
Riley LW, Remis RS, Helgerson SD et al. (1983) Hemorrhagic colitis associated with a rare Escherichia coli serotype. N Engl J Med 308: 681–685
Samuel JE, Perera LP, Ward S, O’Brien AD, Ginsburg V, Krivan HC (1990) Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants. Infect Immun 58: 611–618
Scotland SM, Rowe B, Smith HR, Willshaw GA, Gross RJ (1987) Vero cytotoxin-producing strains of Escherichia coli from children with haemolytic uraemic syndrome and their detec-tion by specific DNA probes. J Med Microbiol 25: 237–243
Spika JS, Parsons JE, Nordenberg D, Wells JG, Gunn RA, Blake PA (1986) Hemolytic uremic syndrome and diarrhea associated with Escherichia coli 0157: H7 in a day care center. J Pediatr 109: 287–291
Stenger K-O, Windier F, Karch H, Wulffen H von, Heesemann J (1988) Hemolytic-uremic syndrome associated with an infection by verotoxin producing Escherichia coli 0111 in a woman on oral contraceptives. Clin Nephrol 29: 153–158
Surawicz CM, Elmer GW, Speelman P, McFarland LV, Chinn J, Belle G van (1989) Prevention of antibiotic-associated diarrhea by saccharomyces boulardii: a prospective study. Gastroenterology 96: 981–988
Tönshoff B, Momper R, Kühl PG, Schweer H, Schärer K, Seyberth HW (1990) Increased thromboxane biosynthesis in childhood hemolytic uremic syndrome. Kidney Int 37: 1134–1141
Toth I, Cohen ML, Rumschlag HS, Riley LW, White EH, Carr JH, Bond WW, Wachsmuth IK (1990) Influence of the 60-megadalton plasmid on adherence of Escherichia coli 0157: H7 and genetic derivatives. Infect Immun 58: 1223–1231
Vial PA, Robins-Browne R, Lior H et al. (1988) Characterization of enteroadherent-aggre-gative Escherichia coli, a putative agent of diarrheal disease. J Infect Dis 158: 70–79
Walters DS, Levin M, Smith C et al. (1988) Intravascular platelet activation in the hemolytic uremic syndrome. Kidney Int 33: 107–115
Weinstein DL, Jackson MP, Samuel JE, Holmes RK, O’Brien AD (1988) Cloning and sequencing of a Shiga-like toxin type II variant from an Escherichia coli strain responsible for Edema disease of swine. J Bacteriol 170: 4223–4230
Wells JG, Davis BR, Wachsmuth IK, Riley LW, Remis RS, Sokolow R, Morris GK (1983) Laboratory investigation of hemorrhagic colitis outbreaks associated with a rare Escherichia coli serotype. J Clin Microbiol 18: 512–520
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Bitzan, M., Karch, H. (1990). Extraintestinale Erkrankungen durch enterohämorrhagische Escherichia coli. In: Ottenjann, R., Müller, J., Seifert, J. (eds) Ökosystem Darm II. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76207-9_23
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DOI: https://doi.org/10.1007/978-3-642-76207-9_23
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