Role of Cellular Adhesion in Rheumatoid Synovitis

Conference paper


The basis for rheumatoid synovitis is a cellular immune response in the sublining tissue of the rheumatoid synovial membrane (RSM). As a consequence of this reaction, cytokines and growth factors are released which mediate a nonspecific amplification of the initial inflammatory focus, proliferation of the synovial tissue, and immunoglobulin and rheumatoid factor synthesis.


Rheumatoid Synovial Membrane Leukocyte Common Antigen Delay Hypersensitivity Reaction Rheumatoid Synovitis Human Umbilical Vein Endothelial Cell Monolayer 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • M. Ziff
    • 1
  1. 1.The University of Texas Southwestern Medical CenterDallasUSA

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