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Chemotherapie des Magenkarzinoms

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Book cover Aktuelle Therapie gastrointestinaler Tumoren

Zusammenfassung

Die Prognose des Magenkarzinoms hat sich in den letzten Jahren nicht entscheidend gebessert. In den UICC-Stadien I und II können 50–80% der Patienten durch eine kurative Resektion geheilt werden [17]. Bei sogenannter kurativer Resektion lokal fortgeschrittener Tumoren (Stadium Illb, IV) beträgt die mediane Überlebenszeit nur 7–12 Monate [16] und bei nicht kurativ resezierbarem, lokal fortgeschrittenen Magenkarzinom oder bei Vorliegen von Fernmetastasen nur 4–(6) Monate [17].

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Literatur

  1. Ajani JA, Goudeau P, Levin B, Faintuch JS, Abbruzzese JL, Boman BM, Kanojia MD (1989) Phase II study of Adriamycin with sequential methotrexate and 5-fluorouracil (AMF) in gastric carcinoma. Cancer Chemother Pharmacol 24:41–44

    Article  PubMed  CAS  Google Scholar 

  2. Arbuck SG, Douglass HO, Nava H, Silk Y, Rustum YM (1989) A phase II trial of 5-FU, Adriamycin, Mitomycin-C and Leucovorin (FAM-CF) in advanced gastric carcinoma. Proc Am Soc of Clin Oncol 8:104, Abstr Nr 402

    Google Scholar 

  3. Beer M, Cavalli F, Kaye SB, Lev LM, Clavel M, Smyth J, van Glabbeke M, Renard J, Pinedo HM (1987) A phase II study of Carboplatin in advanced or metastatic stomach cancer. Eur J Cancer Clin Oncol 23:1565–1567

    Article  PubMed  CAS  Google Scholar 

  4. Berenberg JL, Goodman PJ, Oishi N, Fleming T, Natale RB, Hutchins LH, Guy GT, MacDonald J (1989) 5-Fluorouracil (5-FU) and folinic acid (FA): for the treatment of metastatic gastric cancer. Proc Am Soc Clin Oncol 8:101, Abstr Nr 392

    Google Scholar 

  5. Beretta G, Arnoldi E, Beretta GD, Tedeschi L, Dallavalle G, Bollina R, Fraschini P, Luporini G (1989) A randomized study of Fluorouracil versus FAM polychemotherapy in gastric carcinoma. E.O.R.T.C. Symposium on Advances in Gastrointestinal Tract Cancer Research and Treatment, 48, Nov 1989

    Google Scholar 

  6. De Vries EGE, Greidanus J, Nanningaa A, Verschueren RCJ, Mulder NH, Sleijfer DTh, Willemse PHB (1989) A phase 2 study of a 21-day continuous infusion schedule with Epirubicin in advanced gastric cancer. Proc Am Soc Clin Oncol 8:117, Abstr Nr 455

    Google Scholar 

  7. Fernandes JP, Oliveira J, Santos A, Cunha R, Suosa M, Sequeira M, Gouveia J (1989) Cisplatin (CDDP), Fluorouracil(5-FU) and folinic acid (FOL) in advanced gastric cancer (g.c.). Proc Am Soc Clin Oncol 8:115, Abstr Nr 448

    Google Scholar 

  8. Figer A, Loven D, Vigler N, Ratt P, Walach N, Shani A, Kaplan E, Catane R, Cohen Y (1989) Epirubicin in the treatment of advanced carcinoma of the stomach. Proc Am Soc Clin Oncol 8:112, Abstr Nr 436

    Google Scholar 

  9. Flechtner H, Raech U, Selbach J, Harjung H, Manegold C, Kabelitz K, Trux FA, Edler L, Queißer W (1989) Etoposide, Adriamycin, Cisplatinum (EAP) combination chemotherapy for advanced gastric cancer. Eur Soc Med Oncol 23:106, Abstr Nr 422

    Google Scholar 

  10. Garufi C, Ricevuto E, Grieco A, Astone A, Cassano A, Fontana T, Noviello MR, Barone C (1989) Advanced gastric cancer: response rate and dose intensity with EEP. E.O.R.T.C. Symposium on Advances in Gastrointestinal Tract Cancer Research and Treatment, 51, Strasbourg Nov 1989

    Google Scholar 

  11. Katz A, Gansl R, Simon S, Gama-Rodrigues JJ, Waitzberg D, Bresciani C, Pinotti HV (1989) Phase II trial of VP-16 (V), Adriamycin (A) and Cisplatinum (C) in patients (pts) with advanced gastric cancer (AGC). Proc Am Soc Clin Oncol 8:98, Abstr Nr 378

    Google Scholar 

  12. Kim, DJ, Kim NK, Meng KH, Lee KS, Ahn YO, Kim H-K, Bang YJ (1989) Phase II trial of Carboplatin (CBDCA) in patients with advanced adenocarcinoma of the Stomach. Proc Am Soc Clin Oncol 8:442, Abstr Nr 442

    Google Scholar 

  13. Kim SY, Song MH, Park CS, Lee HY, Kim YK, Lee BH, An BJ (1989) Etoposide, Adriamycin, and Cisplatin (EAP) combination chemotherapy for advanced gastric cancer. J Clin Exper Hematol 59:257, Abstr Nr 51

    Google Scholar 

  14. Kok TC, van der Gaast A, Splinter TAW (1989) Chemotherapy in advanced gastric cancer; different response depending on tumour site. E.O.R.T.C. Symposium on Advances in Gastrointestinal Tract Cancer Research and Treatment, 50, Nov 1989

    Google Scholar 

  15. Lacave AJ, Buesa JM, Gracia JM, Estrada E, Esteban E, Lopes R, Baron FJ, Palacio I (1989) Cisplatin and 5-Fluorouracil in the treatment of advanced gastric cancer. E.O.R.T.C. Symposium on Advances in Gastrointestinal Tract Cancer Research and Treatment, 44, Strasbourg Nov 1989

    Google Scholar 

  16. Meyer H-J, Jähne J, Wilke H (1989) Das organüberschreitende Magenkarzinom. Chir. Gastroenterologie 2:205–212

    Google Scholar 

  17. Preusser P, Achterrath W, Wilke H, Lenaz L, Fink U, Heinicke A, Meyer J, Bünte H (1988) Chemotherapy of gastric cancer. Cancer Treat Rev, 15, 257–277

    Article  PubMed  CAS  Google Scholar 

  18. Preusser P, Wilke H, Achterrath W, Stahl M, Casper J, Meyer H-J, Blum M, Schmoll HJ (1989) Phase II study of Carboplatin in gastric cancer. J Clin Exper Hematol 59:315, Abstr Nr 284

    Google Scholar 

  19. Preusser P, Wilke H, Achterrath W, Fink U, Lenaz L, Heinicke A, Meyer J, Meyer H-J, Bünte H (1989) Phase II study with the combination Etoposide, Doxorubicin, and Cisplatin in advanced measurable castric cancer. J Clin Oncol 7:1310–1317

    PubMed  CAS  Google Scholar 

  20. Rougier Ph, Mahjoubi M, Oliveira J, Tigaud JM, Lasser Ph, Droz JP (1989) Treatment of advanced gastric adenocarcinoma (AGC) with 5-FU/Platinum combination. E.O.R.T.C. Symposium on Advances in Gastrointestinal Tract Cancer Research and Treatment, 45, Strasbourg Nov 1989

    Google Scholar 

  21. Stahl M, Wilke H, Preusser P, Fink U, Achterrath W, Schöber C, Köhne-Wömpner H, Link H, Lenaz L, Meyer H-J, Schmoll H-J, Poliwoda H (1989) Final results of a phase II trial with Etoposide (E), Leucovorin (L), 5-Fluorouracil (F) (ELF) in advanced gastric carcinoma. J Clin Exper Hematol 59:257, Abstr Nr 52

    Google Scholar 

  22. Taguchi T (1989) Combination chemotherapy with Etoposide (E), Adriamycin (A), and Cisplatin (P) (EAP) for advanced gastric cancer. Proc Am Soc Clin Oncol 8:108, Abstr Nr 420

    Google Scholar 

  23. Wils J (1989) Persönliche Mitteilung

    Google Scholar 

  24. Zaniboni A, Simoncini E, Marpicati P, Montini E, Garattini P, Ferragni A, Auzzani A, Boari L, Marini G (1989) Mitomycin-C (MMC), Adriamycin (ADM), 5Fluorouracil (5-FU) and folinic acid (FA) in advanced gastric cancer (GC): preliminary results. Proc Am Soc Clin Oncol 8:107, Abstr Nr 414

    Google Scholar 

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© 1992 Springer-Verlag Berlin Heidelberg

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Preusser, P. et al. (1992). Chemotherapie des Magenkarzinoms. In: Schmoll, HJ., Meyer, HJ., Wilke, H., Pichlmayr, R. (eds) Aktuelle Therapie gastrointestinaler Tumoren. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76187-4_16

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  • DOI: https://doi.org/10.1007/978-3-642-76187-4_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76188-1

  • Online ISBN: 978-3-642-76187-4

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