Non-neoplastic Transitional Epithelium of the Urinary Tract

  • J.-D. Hoppe
  • P. Röttger


Most of the excretory portion of the urinary tract — the renal pelvis and ureter, the bladder except for the trigone, and the proximal part of the urethra — is lined by urothelium. This regional variant of transitional epithelium is distinguished by a superficial layer of “umbrella cells,” large caplike cells that typically cover the intermediate and basal layers of urothelial cells (see Fig. 3.1). The umbrella cells themselves are covered on the luminal side by a mucopolysaccharide layer containing sialic acid and, on scanning electron microscopy, exhibit a network of prominent surface ridges that disappear following certain types of urothelial injury (see Chap. 4).


Urine Sediment Hemorrhagic Cystitis Ileal Conduit Umbrella Cell Cell Spectrum 
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  1. Petersen RO (1992) Urologic pathology. Lippincott, Philadelphia, 2nd EditionGoogle Scholar
  2. Schubert GE (1984) Niere und ableitende Harnwege. In: Remmele W (ed) Pathologie, vol 3. Springer, Berlin Heidelberg New York Tokyo, p 1Google Scholar

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© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • J.-D. Hoppe
  • P. Röttger

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