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Diagnostic DNA Cytometry of the Urothelium

  • A. Böcking

Abstract

The subjective cytologic examination of urinary sediment by no means offers an ideal solution to the diagnosis of bladder carcinoma:
  • The sensitivity is only 70%, depending on the grade of tumor malignancy.

  • The specificity is only 80%–95% (Murphy et al. 1986; Rübben et al. 1989).

  • The reproducibility of malignancy grading, at approximately 60%–70%, is poor (Ooms et al. 1989).

  • The prognostic relevance of the cytologic tumor grade is not adequate to have a definite impact on treatment planning (Böcking et al. 1990).

  • The prospective biologic behavior of dysplastic cells cannot be accurately predicted.

  • The labor cost is high for the screening of large sample volumes in subjects at risk.

Keywords

Transitional Cell Carcinoma Urothelial Carcinoma Bladder Carcinoma Urothelial Cell Bladder Cancer Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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  • A. Böcking

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