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p11, A Member of the S-100 Protein Family, is Associated with the Tyrosine Kinase Substrate p36 (Annexin II)

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Novel Calcium-Binding Proteins

Abstract

While the S-100 proteins have long been known as Ca2+-binding proteins containing typical EF-hand structures (Moore 1965; Isobe et al. 1977), a third member of the still growing S-100 protein family was discovered only a few years ago. Due to its association with the Ca2+-and phospholipid-binding protein p36 (annexin II), p11 was purified from mammalian tissues and shown by sequence analysis to share a high degree of homology with S-l00α and ß.

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  1. Volker Gerke
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  1. Department of Pediatrics Division of Clinical Chemistry, University of Zürich, Steinwiesstraße 75, CH-8032, Zürich, Switzerland

    Claus W. Heizmann

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Gerke, V. (1991). p11, A Member of the S-100 Protein Family, is Associated with the Tyrosine Kinase Substrate p36 (Annexin II). In: Heizmann, C.W. (eds) Novel Calcium-Binding Proteins. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76150-8_9

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  • DOI: https://doi.org/10.1007/978-3-642-76150-8_9

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  • Print ISBN: 978-3-642-76152-2

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