Serum depletion leads to growth arrest of rodent fibroblasts that remain in the Go or quiescent phase of the cell cycle. When serum is added, the cells enter the Go-S transition phase (Figure 1). Five cDNA clones representing sequences that were inducible by serum were isolated by Baserga and coworkers (Hirschorn et al. 1984).
KeywordsAcute Myeloid Leukemia Calcium Binding Protein Ehrlich Ascites Tumor Cell Prolactin Receptor Partial Amino Acid Sequence
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