Abstract
Two types of information are needed for an objective assessment of immunomodulatory (IM) activities of a drug: data on functional alterations of all basic elements of the immune system caused by the drug (as revealed by a panel of in vitro/ex vivo tests), and on its overall impact on resistance. The latter purpose is served by experimental models of infections or transplantable tumors.In this paper we present results of a comparative study evaluating immunostimulatory potency of three microbial and two synthetic preparations in a mouse model of an acute bacterial infection.
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© 1990 Springer-Verlag Berlin Heidelberg
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Franěk, J., Malina, J. (1990). Immunomodulatory Capacity of Drugs Evaluated in a Mouse Model of Klebsiella pneumoniae Infection. In: Masihi, K.N., Lange, W. (eds) Immunotherapeutic Prospects of Infectious Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76120-1_6
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DOI: https://doi.org/10.1007/978-3-642-76120-1_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-76122-5
Online ISBN: 978-3-642-76120-1
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