The Biology of the Connective Tissue of the Human Optic Nerve Head

  • M. R. Hernandez
  • A. H. Neufeld
Conference paper

Abstract

Over the past several years, we have characterized the macromolecular components of the extracellular matrix of the lamina cribrosa of the human optic nerve head. We have hypothesized that age-related changes and individual differences in the molecular composition of this tissue may underlie the glaucomatous process and contribute to the degeneration of optic nerve fibers. This chapter will review some of the data that we have presented in support of this hypothesis.

Keywords

Permeability Fibril Macromolecule Glaucoma Compressibility 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • M. R. Hernandez
    • 1
  • A. H. Neufeld
    • 1
  1. 1.BostonUSA

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