A Comparison of Treated and Untreated Glaucoma Suspects

  • S. M. Drance
  • G. R. Douglas
  • M. Schulzer
Conference paper

Abstract

The causal relationship of elevated intraocular pressure and glaucoma-like changes at the optic nerve head has been established [1]. Anderson [2] in his Jackson lecture examined the relationship of intraocular pressure and open-angle glaucoma. The notion that other risk factors must also be present was restated. The evidence for success with medial pressure reduction in damaged glaucoma eyes is still controversial [3–12], although the evidence that surgical pressure reduction favorably influences progression is established [13, 14].

Keywords

Sugar Depression Eter Peri Epinephrine 

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References

  1. 1.
    Quigley HA, Addicks EM (1980) Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport. Invest Ophthalmol Vis Sci 19:137–152PubMedGoogle Scholar
  2. 2.
    Anderson, DR (1989) Glaucoma: The damage caused by pressure. Am J Ophthalmol 108:485–495PubMedGoogle Scholar
  3. 3.
    Becker B, Morton WR (1966) Topical epinephrine in glaucoma suspects. Am J Ophthalmol 62:272–277PubMedGoogle Scholar
  4. 4.
    Shin DH, Kolker AE, Kass MA, Kaback MB, Becker B (1976) Long-term epinephrine therapy of ocular hypertension. Arch Ophthalmol 94:2059–2060PubMedCrossRefGoogle Scholar
  5. 5.
    Kitazawa Y (1981) Prophylactic therapy of ocular hypertension: A prospective study. Trans Ophthalmol Soc NZ 33:30–32Google Scholar
  6. 6.
    Krug HJ Jr, Hertzmark E, Remis LL, Epstein D (1987) Long-term study of timolol versus no treatment in the management of glaucoma suspects. Invest Ophthalmol Vis Sci 28 (suppl): 148Google Scholar
  7. 7.
    Graham PA (1969) The definition of pre-glauco-ma: A prospective study. Eye 88:153–165Google Scholar
  8. 8.
    Norskov K (1970) Routine tonometry in ophthalmic practice: II, five-year follow-up. Acta Ophthalmol 48:873–895Google Scholar
  9. 9.
    Levene RZ (1975) Uniocular miotic therapy. Ophthalmology 79:376–380Google Scholar
  10. 10.
    David R, Livingston DG, Luntz MH (1977) Ocular hypertension: A long-term follow-up of treated and untreated patients. Br J Ophthalmol 61:668–674PubMedCrossRefGoogle Scholar
  11. 11.
    Chauhan BC, Drance SM, Douglas GR (1988) The effect of long-term intraocular pressure reduction on the differential light sensitivity in glaucoma suspects. Invest Ophthalmol Vis Sci 29:1478–1485PubMedGoogle Scholar
  12. 12.
    Chisholm IA, Stead S, Tan L, Melenchuk JW (1980) Prognostic indicators in ocular hypertension. Can J Ophthalmol 15:4–8PubMedGoogle Scholar
  13. 13.
    Werner EB, Drance SM, Schulzer M (1977) Trabeculectomy and the progression of glaucomatous visual field loss. Arch Ophthalmol 105: 774–6Google Scholar
  14. 14.
    Dake CL, Greve EL (1979) Four year follow-up of glaucoma operation. Int Ophthalmol 1: 139–145PubMedCrossRefGoogle Scholar
  15. 15.
    Nagin P, Schwartz B, Nanba K (1985) Detection of increased pallor over time. Computerized image analysis in untreated ocular hypertension. Ophthalmology 92:252–260PubMedGoogle Scholar
  16. 16.
    Armaly MF, Krueger DE, Maunder L, Becker B, Hetherington J Jr, Kolker AE (1980) Biosta-tistical analysis of the collaborative glaucoma study. Arch Ophthalmol 98:2163–2171PubMedCrossRefGoogle Scholar
  17. 17.
    SAS Institute Inc. SAS User Guide: Statistics, Version 5 Ed. Cary NC (1985) SAS Institute Inc. 433–506Google Scholar
  18. 18.
    Zimmerman TJ, Kaufman HE (1977) Timolol: A -adrenergic blocking agent for the treatment of glaucoma. Arch Ophthalmol 95:601–604PubMedCrossRefGoogle Scholar
  19. 19.
    Radius RL, Diamond GR, Pollack IP, Langham ME (1978) Timolol: A new drug for management of chronic simple glaucoma. Arch Ophthalmol 96:1003–1008PubMedCrossRefGoogle Scholar
  20. 20.
    Wilson RP, Kanal N, Spaeth GL (1978) Timolol: Its effectiveness in different types of glaucoma. Ophthalmology 86:43–50Google Scholar
  21. 21.
    Epstein DL, Krug JH, Hertzmark E, Remis LL, Edelstein DJ (1989) A long-term clinical trial of timolol therapy versus no treatment in the management of glaucoma suspects. Ophthalmol 96: 10; 1460–1467Google Scholar
  22. 22.
    Kass MA, Gordon MO, Hoff MR, Parkinson JM, Kolker AE, Hart WM, Becker B (1989) Topical timolol administration reduced the incidence of glaucomatous damage in ocular hypertensive individuals. Arch Ophthalmol 107: 1590–1598PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • S. M. Drance
    • 1
  • G. R. Douglas
    • 1
  • M. Schulzer
    • 1
  1. 1.VancouverCanada

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