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Immunochemistry of Candida Mannans

  • Conference paper
Fungal Cell Wall and Immune Response

Part of the book series: NATO ASI Series ((ASIH,volume 53))

Abstract

The first description on the serological heterogeneity in C. albicans was published by Hasenclever and Mitchell (1961). These workers revealed that this species could be classified into two serotypes, A and B, as judged from the results of agglutination assay between the cells of large number of C. albicans strains and anti-rabbit whole cell sera. These workers (1964) identified the chemical entity of antigen of C. albicans as a water-soluble mannan, based on its ability to inhibit the agglutination reactions Summers et al. (1964) reported that the mannans of C. albicans serotype B strains were more cross-reactive with the anti-whole cell serum of Saccharomyces cerevisiae than the mannans of serotype A strains. Tsuchiya and his co-workers undertook a serological classification of a variety of yeasts, based on agglutination assays among heat-killed yeast form cells and polyclonal anti-rabbit whole cell sera absorbed with the heat-killed whole cells of the other Candida strains. They reported the presence of 14 different serotypes in the seven medically important Candida species (Tsuchiya et al, 1955, 1974).

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Authors and Affiliations

  1. Tohoku College of Pharmacy, Sendai, Japan

    S. Suzuki, N. Shibata & H. Kobayashi

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  1. S. Suzuki
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  2. N. Shibata
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  3. H. Kobayashi
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Editors and Affiliations

  1. Institut Pasteur, Unité de Mycologie, 25, rue du Dr. Roux, 75724, Paris Cedex 15, France

    J. P. Latgé

  2. Dept. of Entomology and Nematology, University of Florida, 32611-0711, Gainesville, FL, USA

    D. Boucias

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© 1991 Springer-Verlag Berlin Heidelberg

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Suzuki, S., Shibata, N., Kobayashi, H. (1991). Immunochemistry of Candida Mannans. In: Latgé, J.P., Boucias, D. (eds) Fungal Cell Wall and Immune Response. NATO ASI Series, vol 53. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76074-7_9

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  • DOI: https://doi.org/10.1007/978-3-642-76074-7_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76076-1

  • Online ISBN: 978-3-642-76074-7

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