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Fungal Wall Components and Immunostimulation

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Fungal Cell Wall and Immune Response

Part of the book series: NATO ASI Series ((ASIH,volume 53))

Abstract

Fungi or components thereof, when introduced into appropriate hosts, can induce antigen-specific immune responses as well as stimulate non-specific antigen-independent events, either of which can be enhancing or suppressive. Two yeasts in particular have been investigated for their ability to interact with the immune system, viz., Saccharomyces cerevisiae and Candida albicans. The former has been investigated predominantly for its ability to enhance responses in a non-specific manner, and the latter for its ability to enhance or suppress both specific and non-specific responses. This review, however, is confined to the stimulatory phenomena resulting in enhancement. Moreover, this presentation will be focused on one of the four major components of the yeast wall, mannan (MAN), either as a homopolymer or as a heteropolymer combined with other wall constituents such as glucan or chitin.

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Author information

Authors and Affiliations

  1. Tulane University, New Orleans, Louisiana, USA

    J. E. Domer

  2. Mercer University, Macon, Georgia, USA

    R. E. Garner

Authors
  1. J. E. Domer
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  2. R. E. Garner
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Editor information

Editors and Affiliations

  1. Institut Pasteur, Unité de Mycologie, 25, rue du Dr. Roux, 75724, Paris Cedex 15, France

    J. P. Latgé

  2. Dept. of Entomology and Nematology, University of Florida, 32611-0711, Gainesville, FL, USA

    D. Boucias

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© 1991 Springer-Verlag Berlin Heidelberg

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Domer, J.E., Garner, R.E. (1991). Fungal Wall Components and Immunostimulation. In: Latgé, J.P., Boucias, D. (eds) Fungal Cell Wall and Immune Response. NATO ASI Series, vol 53. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76074-7_31

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  • DOI: https://doi.org/10.1007/978-3-642-76074-7_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76076-1

  • Online ISBN: 978-3-642-76074-7

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