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Cell Wall Related Antigens and Dermatophyte Infections

  • Conference paper
Fungal Cell Wall and Immune Response

Part of the book series: NATO ASI Series ((ASIH,volume 53))

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Abstract

In contrast to most other fungi which produce disease in man, dermatophytes exhibit a parasitic mode of existence and are dependent on infection in human for their survival (Rippon, 1982). Dermatophytes are well adapted to parasitize the stratum corneum, hair and nails using specific keratinases (Grzywnowicz et al., 1989). Invasion and infection of other organs does not occur. Presently, approximately 41 species of Dermatophytes belonging to the genera Epidermophyton (2), Microsporum (17) and Trichophyton (22) are recognized. Colonization by dermatophytes begins in the horny layer of the skin. The host reaction varies from slight scaling to eczematous dermatitis or even more serious inflammation (kerion celsi). The inflammatory reactions are usually not seen during the first weeks after infestation. In most cases, the clinical symptoms disappear after some time (acute dermatophytosis). In certain instances dermatophytic infection in spite of treatment, persists for years and years (chronic dermatophytosis).

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Authors and Affiliations

  1. Free University, Amsterdam, The Netherlands

    P. de Haan, C. Nieboer, E. M. H. van der Raay-Helmer & D. M. Boorsma

Authors
  1. P. de Haan
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  2. C. Nieboer
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  3. E. M. H. van der Raay-Helmer
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  4. D. M. Boorsma
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Editor information

Editors and Affiliations

  1. Institut Pasteur, Unité de Mycologie, 25, rue du Dr. Roux, 75724, Paris Cedex 15, France

    J. P. Latgé

  2. Dept. of Entomology and Nematology, University of Florida, 32611-0711, Gainesville, FL, USA

    D. Boucias

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© 1991 Springer-Verlag Berlin Heidelberg

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de Haan, P., Nieboer, C., van der Raay-Helmer, E.M.H., Boorsma, D.M. (1991). Cell Wall Related Antigens and Dermatophyte Infections. In: Latgé, J.P., Boucias, D. (eds) Fungal Cell Wall and Immune Response. NATO ASI Series, vol 53. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76074-7_28

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  • DOI: https://doi.org/10.1007/978-3-642-76074-7_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76076-1

  • Online ISBN: 978-3-642-76074-7

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