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Carbon Monoxide Poisoning: Physico-Chemical Principles and Environmental Applications

  • N. M. Senozan
Conference paper
Part of the NATO ASI Series book series (volume 31)

Abstract

Carbon monoxide has been called a pedagogical poison because its mechanism of action is simple and can be taught in introductory chemistry, biology and health sciences. Carbon monoxide’s affinity for hemoglobin is 220 times greater than that of oxygen and an exposure to a partial carbon monoxide pressure of only 1 mm Hg replaces more than half the oxygen on hemoglobin with CO*. A person in an atmosphere with 0.05% CO dies in eight hours, at a concentration of 0.1% death comes within an hour (Shephard, 1983; Ellenhorn and Barceloux, 1988).

Keywords

Carbon Monoxide Oxygen Transport Fractional Saturation Oxyhemoglobin Dissociation Curve Carboxyhemoglobin Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

CO

carbon monoxide

O2

oxygen

COHb

carboxyhemoglobin

MWC

Monod Wyman and Changeux

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • N. M. Senozan
    • 1
  1. 1.Department of Chemistry and BiochemistryCalifornia State UniversityLong BeachUSA

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