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Some Factors Affecting N-Nitroso Compound Formation from Ingested Nitrate in the Stomach: Achlorhydria, Bacterial N-Nitrosation and its Modulation

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Part of the book series: NATO ASI Series ((ASIG,volume 30))

Abstract

Bacterial N-nitrosation and nitrate reduction in the mouth and achlorhydric stomach may play an important role in determining the carcinogenic risk of nitrate exposure through N-nitroso compound (NNC) formation. The factors known to modulate the extent of these two processes are numerous, and through their differential action between individuals may promote profound differences in levels of NNC formation from particular levels of nitrate exposure. It may be difficult at present to allow for this in epidemiological studies.

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© 1991 Springer-Verlag Berlin Heidelberg

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Leach, S., Mackerness, C., McPherson, K., Packer, P., Hill, M., Thompson, M. (1991). Some Factors Affecting N-Nitroso Compound Formation from Ingested Nitrate in the Stomach: Achlorhydria, Bacterial N-Nitrosation and its Modulation. In: Bogárdi, I., Kuzelka, R.D., Ennenga, W.G. (eds) Nitrate Contamination. NATO ASI Series, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76040-2_24

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  • DOI: https://doi.org/10.1007/978-3-642-76040-2_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76042-6

  • Online ISBN: 978-3-642-76040-2

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