Prognostic Significance of EEG Sleep Changes in Late-Life Depression
Our studies of EEG sleep changes in late-life depression have shown that these alterations have both diagnostic and prognostic significance, particularly for understanding patients with mixed clinical presentations of both depression and cognitive impairment. More recently, our work has also suggested that certain sleep changes may be associated with higher risk for recurrence of depression in late life, as well as with higher risk of mortality within 2 years. In this report, we discuss data from several ongoing and interrelated studies of sleep, aging, and depression.
KeywordsNREM Sleep Total Sleep Deprivation Depressive Pseudodementia Systemic Medical Illness
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