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Health Risk of Insomnia

  • D. F. Kripke
  • S. Ancoli-Israel
  • R. L. Fell
  • W. J. Mason
  • M. R. Klauber
  • O. Kaplan
Conference paper

Abstract

An unexpected result appeared in the American Cancer Society’s Cancer Prevention Study I [1, 2]. Over one million volunteers had completed health questionnaires and were followed prospectively for 6 years. Those who said that they “usually get” 7–8 h sleep a night had the best survival rates. Volunteers who reported sleeping less than 7 h or more than 8 h had higher mortality rates. The same significant trend appeared in both sexes and in each of 13 age groups from 30–35 to over 90 years. However, the trends were most marked among subjects over 60 [2, 3]. Indeed, since most adult deaths occur in the elderly, 86% of the excess deaths associated with short or long reported sleep occurred among subjects over 60 at the start of follow-up. Among such subjects, 3.8% of all deaths were associated with long or short sleep, making this a rather powerful predictor, comparable to obesity, as a mortality risk factor.

Keywords

Obstructive Sleep Apnea Sleep Apnea Obstructive Sleep Apnea Syndrome Sleep Duration Total Sleep Time 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Hammond EC (1964) Some preliminary findings on physical complaints from a prospective study of 1.064.004 men and women. Am J Public Health 54: 11–24CrossRefGoogle Scholar
  2. 2.
    Kripke DF, Simons RN, Garfinkel L, Hammond EC (1979) Short and long sleep and sleeping pills: is increased mortality associated? Arch Gen Psychiatry 36: 103–116PubMedGoogle Scholar
  3. 3.
    Kripke DF, Ancoli-Israel S, Mason W, Messin S (1983) Sleep related mortality and morbidity in the aged. In: Chase MH, Weitzman ED (eds) Sleep disorders: basic and clinical research. Spectrum, New York pp 415–429Google Scholar
  4. 4.
    Wingard DL, Berkman LF (1983) Mortality risk associated with sleeping patterns among adults. Sleep 6: 102–107PubMedGoogle Scholar
  5. 5.
    Branch LG, Jette AM (1984) Personal health practices and mortality among the elderly. Am J Public Health 74: 1126–1129PubMedCrossRefGoogle Scholar
  6. 6.
    Partinen M, Putkonen PTS, Kaprio J, Koskenvuo M, Hilakivi I (1988) Sleep disorders in relation to coronary heart disease. Acta Med Scand (Suppl) 660: 69–83Google Scholar
  7. 7.
    Wingard DL, Berkman LF, Brand RJ (1982) A multivariate analysis of health-related practices. Am J Epidemiol 116: 765–775PubMedGoogle Scholar
  8. 8.
    Kripke DF (1985) Chronic hypnotic use: the neglected problem. In: Koella WP, Ruther E, Schulz H (eds) Sleep ’84 Fischer, Stuttgart, pp 338–340Google Scholar
  9. 9.
    Morgan K, Dallosso H, Ebrahim S, Arie T, Fentem PH (1988) Prevalence, frequency and duration of hypnotic drug use among the elderly living at home. Br Med J 296: 601–602CrossRefGoogle Scholar
  10. 10.
    Kripke DF, Garfinkel L (1984) Excess nocturnal deaths related to sleeping pill and transquilliser use. Lancet I: 99CrossRefGoogle Scholar
  11. 11.
    Kripke DF, Ancoli-Israel S (1983) Epidemiology of sleep apnea among the aged: is sleep apnea a fatal disorder? In: Guilleminault C, Lugaresi E (eds) Sleep/wake disorders: natural history, epidemiology, and long-term evolution. Raven, New York, pp 137–142Google Scholar
  12. 12.
    Kripke DF, Ancoli-Israel S, Mason WJ, Kaplan O (1990) Sleep apnea: association with deviant sleep durations and increased mortality. In: Guilleminault C, Partinen M (eds) Obstructive sleep apnea syndrome: clinical research and treatment. Raven, New York, pp 9–14Google Scholar
  13. 13.
    Guilleminault C, Eldridge FL, Dement WC (1973) Insomnia with sleep apnea: a new syndrome. Science 181: 856–858PubMedCrossRefGoogle Scholar
  14. 14.
    Kales A, Bixler EO, Soldatos CR, Vela-Bueno A, Caldwell AB, Cadieux RJ (1982) Biopsychobehavioral correlates of insomnia. Part I. Role of sleep apnea and nocturnal myoclonus. Psychosomatics 23: 589–600PubMedGoogle Scholar
  15. 15.
    Roehrs T, Conway W, Wittig R, Zorick F, Sicklesteel J, Roth T (1985) Sleep-wake complaints in patients with sleep-related respiratory disturbances. Am Rev Respir Dis 132: 520–523PubMedGoogle Scholar
  16. 16.
    Weitzman ED (1979) The syndrome of hypersomnia and sleep-induced apnea. Chest 75: 414–415PubMedCrossRefGoogle Scholar
  17. 17.
    Lugaresi E, Coccagna G (1980) Hypersomnia with periodic apneas. Z EEG EMG 11: 167–72Google Scholar
  18. 18.
    Lugaresi E, Coccagna G, Mantovani M (1978) Hypersomnia with periodic apneas. In: Weitzman ED (ed) Advances in sleep research, vol 4. Spectrum, New York, pp 1–151Google Scholar
  19. 19.
    Dolly FR, Block AJ (1982) The effect of flurazepam on sleep-disordered breathing and nocturnal oxygen desaturation in asymptomatic subjects. Am Rev Respir Dis 125: 107Google Scholar
  20. 20.
    Mendelson WB, Garnett D, Gillin JC (1981) Single case study: flurazepam-induced sleep apnea syndrome in a patient with insomnia and mild sleep-related respiratory changes. J Nerv Ment Dis 169: 261–264PubMedCrossRefGoogle Scholar
  21. 21.
    Ancoli-Israel S, Klauber MR, Kripke DF, Parker L, Cobarrubias M (1989) Sleep apnea in female patients in a nursing home: increased risk of mortality. Chest 96 (5): 1054–1058PubMedCrossRefGoogle Scholar
  22. 22.
    He J, Kryger MH, Zorick FJ, Conway W, Roth T (1988) Mortality and apnea index in obstructive sleep apnea: experience in 385 male patients. Chest 94: 9–14PubMedCrossRefGoogle Scholar
  23. 23.
    Ancoli-Israel S, Kripke DF, Mason W, Kaplan OJ (1985) Sleep apnea and periodic movements in an aging sample. J Gerontol 40: 419–425PubMedGoogle Scholar
  24. 24.
    Ancoli-Israel S, Kripke DF, Mason W (1987) Characteristics of obstructive and central sleep apnea in the elderly: an interim report. Biol Psychiatry 22: 741–750PubMedCrossRefGoogle Scholar
  25. 25.
    Ancoli-Israel S, Kripke DF, Mason W, Messin S (1981) Comparisons of home sleep recordings and polysomnograms in older adults with sleep disorders. Sleep 4: 283–291PubMedGoogle Scholar
  26. 26.
    Mason WJ, Kripke DF, Messin S, Ancoli-Israel S (1986) The application and utilization of an ambulatory recording system for the screening of sleep disorders. Am J EEG Technol 26: 145–146Google Scholar
  27. 27.
    Ancoli-Israel S (1988) The use of a modified Respitrace/Medilog portable system in the evaluation of sleep apnea. J Amb Mon 1 (4): 267–278Google Scholar
  28. 28.
    Ancoli-Israel S, Parker L, Sinaee R, Fell R, Kripke DF (1989) Sleep fragmentation in patients from a nursing home. J Gerontol 44: M18–M21PubMedGoogle Scholar
  29. 29.
    Mason WJ, Ancoli-Israel S, Kripke DF (1989) Apnea revisited: a longitudinal follow-up. Sleep 12 (5): 423–429PubMedGoogle Scholar
  30. 30.
    Mosko SS, Dickel MJ, Ashurst J (1988) Night-to-night variability in sleep apnea and sleep in sleep-related periodic leg movements in the elderly. Sleep 11: 340–348PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • D. F. Kripke
  • S. Ancoli-Israel
  • R. L. Fell
  • W. J. Mason
  • M. R. Klauber
  • O. Kaplan
    • 1
    • 2
  1. 1.Department of Psychiatry, V-116-AVeterans Administration Medical CenterSan DiegoUSA
  2. 2.University of CaliforniaSan DiegoUSA

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