Abstract
The minimum (nadir) arterial oxyhemoglobin saturation (SaO2) during obstructive sleep apnea (OSA) is a function of apnea duration and rate of fall of arterial oxyhemoglobin saturation (dSaO2/dt) (Fig. 1). The longer the apnea, or the steeper the dSaO2/dt for a given duration of apnea, the lower the nadir SaO2 will be. Several factors have been shown to affect apnea duration: hypercarbia [1], level of oxygenation [1–4], and stage of sleep [5]. Other studies have demonstrated that dSaO2/dt is affected by thoracic gas volume [6, 7] as well as SaO2 [8, 9] at apnea onset.
Supported by the General Research Service of the Veterans Administration.
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© 1991 Springer-Verlag Berlin Heidelberg
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Fletcher, E.C. (1991). Central Venous Oxygen Saturation, Abnormal Gas Exchange, and Rate of Fall of Arterial Oxyhemoglobin Saturation During Obstructive Apnea. In: Peter, J.H., Penzel, T., Podszus, T., von Wichert, P. (eds) Sleep and Health Risk. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76034-1_22
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DOI: https://doi.org/10.1007/978-3-642-76034-1_22
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