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Pathogenesis

  • Chapter
Bunyaviridae

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 169))

Abstract

The family Bunyaviridae consists of over 250 individual virus species grouped into five genera. Most of these viruses rarely infect humans or domestic animals. This chapter focuses on the few viruses that are important pathogens

Table 1 Selected bunyaviruses that cause disease in humans or domestic animals
Full size table

and which have been studied in experimental vertebrate hosts. Particular emphasis is given to the California serogroup since this group of agents has received the most detailed analysis. Several other viruses, such as Rift Valley fever virus, Hantaan virus, and Crimean-Congo hemorrhagic fever virus are important causes of disease but are difficult to study because they require special containment facilities and because of a paucity of animal models which mimic the human disease

Table 2 Animal models for selected pathogenic bunyaviruses
Full size table

. A summary is presented of the information available on these agents.

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  1. Departments of Neurology and Microbiology, School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA

    F. Gonzalez-Scarano, M. J. Endres & N. Nathanson

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  1. F. Gonzalez-Scarano
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  1. School of Medicine, C.M.U., University of Geneva, Avenue de Champel 9, 1211, Geneva 4, Switzerland

    Daniel Kolakofsky (Professor of Microbiology) (Professor of Microbiology)

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Gonzalez-Scarano, F., Endres, M.J., Nathanson, N. (1991). Pathogenesis. In: Kolakofsky, D. (eds) Bunyaviridae. Current Topics in Microbiology and Immunology, vol 169. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76018-1_8

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