Behandlung bulimischer Eßstörungen mit Antidepressiva

  • M. M. Fichter
Conference paper

Zusammenfassung

Bulimia nervosa ist nach den DSM-III-R-Kriterien (American Psychiatric Association 1987) durch das Vorliegen folgender Symptome definiert:
  1. a)

    Wiederholte Episoden von „Freßattakken“, raschem Verzehr einer großen Nahrungsmenge in einer relativ kurzen Zeit (gewöhnlich weniger als 2 h),

     
  2. b)

    während der „Freßattacken“ besteht das Gefühl, keine Kontrolle mehr über das Eßverhalten zu haben,

     
  3. c)

    regelmäßiges selbst herbeigeführtes Erbrechen oder Mißbrauch von Laxanzien oder rigorose Diäten oder Fasten um den Auswirkungen der „Freßattacken“ entgegenzusteuern,

     
  4. d)

    ein durchschnittliches Minimum von 2 „Freßattacken“ pro Woche über mindestens 3 Monate und

     
  5. e)

    persistierende Zentriertheit auf Körperfigur und -gewicht.

     

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Agras WS, Dorian B, Kirkley BG, Anrow B, Bachman J (1987) Imipramine in the treatment of bulimia: A double-blind controlled study. Int J Eating Dis 6:29CrossRefGoogle Scholar
  2. American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders, 34th edn (DSM-III-R). American Psychiatric Association, Washington DCGoogle Scholar
  3. Blouin AG, Blouin JH, Perez EL, Bushnik T, Zuro C, Mulder E (1988) Treatment of bulimia with fenfluramine and desipramine. J Clin Psychopharmacol 8:261PubMedCrossRefGoogle Scholar
  4. Brotman AW, Herzog DB, Woods SW (1984) Anti-depressant treatment of bulimia. The relationship between bingeing and depressive symptomatology. J Clin Psychiatry 47:7Google Scholar
  5. Chevlan EM (1984) The adjunctive use of lithium carbonate in the management of bulimia resistant to antidepressant therapy. Presented at the First International Conference on Eating Disorders, New YorkGoogle Scholar
  6. Cole W, Lapierre YD (1986) The use of tryptophan in normal-weight bulimia. Can J Psychiatry 31:755PubMedGoogle Scholar
  7. Crane RA, Raskin V, Weiler M, Ferri J, Jobe TH, Anderson J, Burg B (1970) Nomifensine treatment of bulimia: Results of an open trial. Int J Eating Disord 6:427CrossRefGoogle Scholar
  8. Damlouji NF, Ferguson JM (1984 a). Trazodone-induced delirium in bulimic patients. Am J Psychiatry 141:434PubMedGoogle Scholar
  9. Damlouji NF, Ferguson JM (1984 b) Trazodone in the treatment of bulimic patients. Paper presented at the First International Conference on Eating Disorders, New YorkGoogle Scholar
  10. Fairburn CG (1985) Cognitive-behavioral treatment for bulimia. In: Garner DM, Garfinkel PE (eds) Handbook of psychotherapy for anorexia nervosa and bulimia. Guilford Press, London New York p. 160Google Scholar
  11. Ferguson JM (1987) Treatment of an anorexia nervosa patient with fluoxetine. Am J Psychiatry 144:1239PubMedGoogle Scholar
  12. Fichier MM, Leibl K, Rief W, Brunner E u. Engel R (im Druck) Fluoxetine versus placebo: A double-blind study with inpatients receiving intensive psychotherapy. PsychopharmacologyGoogle Scholar
  13. Freeman CPL (1986) Fluoxetine treatment for bulimia. Presented at the Second International Conference on Eating Disorders, New YorkGoogle Scholar
  14. Freeman CPL, Davies F, Morris J, Cheshire K, Hampson M (Publikation in Vorbereitung) A double-blind controlled trial of fluoxetine versus placebo for bulimia nervosaGoogle Scholar
  15. Green RS, Rau JH (1977) The use of diphenylhydantoin in compulsive eating disorders: Further studies. In: Vigersky RA (ed) Anorexia nervosa. Raven Press, New York, p 377Google Scholar
  16. Greenway FL, Dahms WT, Brag DA (1977) Phenytoin as a treatment of obesity associated with compulsive eating. Curr Ther Res 21:338Google Scholar
  17. Herridge PL, Pope HG jr (1985) Treatment of bulimia and rapid-cycling bipolar disorder with sodium valproate. J Clin Psychopharmacol 5:229PubMedCrossRefGoogle Scholar
  18. Horne RL (1984) Bupropion in the treatment of bulimia. Presented at the First International Conference on Eating Disorders, New YorkGoogle Scholar
  19. Hsu LKG (1984) Treatment of bulimia with lithium. Am J Psychiatry 141:1260PubMedGoogle Scholar
  20. Hudson JI, Pope HG (1990) Psychopharmacological treatment of bulimia. In: Fichter MM (ed) Bulimia nervosa: Basic research, diagnosis and therapy. Wiley, ChichesterGoogle Scholar
  21. Hughes PL, Wells LA, Cunningham CJ, Ilstrup DM (1986) Treating bulimia with desipramine: A placebo-controlled double-blind study. Arch Gen Psychiatry 43:182PubMedGoogle Scholar
  22. Jonas JM, Gold MS (1986) Naltrexone reserves bulimic symptoms. Lancet I: 807CrossRefGoogle Scholar
  23. Jonas JM, Gold MS (1987) Treatment of antidepressant-resistant bulimia with naltrexone. Int J Psychiat Med 16:305CrossRefGoogle Scholar
  24. Kaplan AS, Garfinkel PE, Garner DM (1987) Bulimia treated with carbamazepine and imipramine. Presented at American Psychiatric Association Annual Meeting, ChicagoGoogle Scholar
  25. Kaplan AS, Garfinkel PE, Darby PL, Garner DM (1987) Carbamazepine in the treatment of bulimia. Am J Psychiatry 140:1225Google Scholar
  26. Kennedy SH, Piran N, Garfinkel PE (1985) Monoamine oxidase inhibitor therapy for anorexia nervosa and bulimia: A preliminary trial of isocarboxazid. J Clin Psychopharmacol 5:279PubMedCrossRefGoogle Scholar
  27. Kennedy SH, Piran N, Warsh RR, Prendergast P, Mainprize E, Whynot C, Garfinkel PE (in press) A trial of isocarboxazid in the treatment of bulimia. J Clin PsychopharmacolGoogle Scholar
  28. Krahn D, Mitchell J (1985) Use of L-tryptophan in treating bulimia. Am J Psychiatry 142:1130PubMedGoogle Scholar
  29. Levine LR, Pope HG, Enas GG et al., the Fluoxetine Bulimia Collaborative Study Group (Veröffentlichung in Vorbereitung). Fluoxetine in the treatment of bulimia nervosa: A multicenter placebo-controlled double-blind trialGoogle Scholar
  30. Mc Elroy SL, Keck PE jr, Pope HG jr(1987). Sodium valproate: Its use in primary psychiatric disorders. J Clin Psychopharmacol 7:16Google Scholar
  31. Mendels J(1983) Eating disorders and antidepressants. J Clin Psychopharmacol 3:59CrossRefGoogle Scholar
  32. Mitchell JE, Groat R (1984) A placebo-controlled, double-blind trial of amitriptyline in bulimia. J Clin Psychopharmacol 4:186PubMedCrossRefGoogle Scholar
  33. Mitchell JE, Laine DE, Money JE, Levine AS (1986) Naloxone but not CCK-8 may attenuate binge-eating behavior in patients with the bulimia-syndrome. Biol Psychiatry 21:1399PubMedCrossRefGoogle Scholar
  34. Mitchell (1988) In: Pirke KM, Vandereycken W, Ploog D (eds) The psychobiology of bulimia nervosa. Springer, Berlin Heidelberg-New York TokyoGoogle Scholar
  35. Moore DC (1977) Amitriptyline therapy in anorexia nervosa. Am J Psychiatry 134:1303PubMedGoogle Scholar
  36. Nassr DG (1986) Successful treatment of bulimia with no mifensine. Am J Psychiatry 143:373PubMedGoogle Scholar
  37. Ong YL, Checkley SA, Russell GFM (1983) Suppression of bulimic symptoms with methylamphetamine. Br J Psychiatry 143:288PubMedCrossRefGoogle Scholar
  38. Pope HG jr, Hudson JI (1982) Treatment of bulimia with antidepressants. Psychopharmacology 78:167CrossRefGoogle Scholar
  39. Pope HG jr, Hudson JI (1986) Antidepressant drug therapy of bulimia: Current status. J Clin Psychiatry 47:339PubMedGoogle Scholar
  40. Pope HG jr, Hudson JI, Jonas JM (1983) Antidepressant treatment of bulimia: Preliminary experience and practical recommendations. J Clin Psychopharmacol 3:274PubMedGoogle Scholar
  41. Pope HG jr, Hudson JI, Jonas JM, Yurgelun-Todd (1983) Bulimia treated with Imipramine. A placebo-controlled, double-blind study. Am J Psychiatry 140:554PubMedGoogle Scholar
  42. Pope HG jr, Herridge PL, Hudson JI, Fontaine R (1986) Treatment of bulimia with nomifensine. Am J Psychiatry 143:371PubMedGoogle Scholar
  43. Pope HG jr, Champoux RF, Hudson JI (1987) Eating disorder and socioeconomic class. Anorexia nervosa and bulimia in nine communities. J Nerv Ment Dis 175:620–623PubMedCrossRefGoogle Scholar
  44. Rau JH, Green RS (1978) Soft neurological correlates of compulsive eating. J Nerv Ment Dis 166:435PubMedCrossRefGoogle Scholar
  45. Rau JH, Struve FA, Green RS (1979) Electroencephalographic correlates of compulsive eating. Clin Electroencephalogr 10:180PubMedGoogle Scholar
  46. Rich CL (1978) Self-induced vomiting. Psychiatric considerations. JAMA 239:2688PubMedCrossRefGoogle Scholar
  47. Robinson PH, Checkley SA, Russell GFM (1985) Suppression of eating by fenfluramine in patients with bulimia nervosa. Br J Psychiatry 146:169PubMedCrossRefGoogle Scholar
  48. Roy-Byrne P, Gwirtsman H, Edelstein CK, Yager J, Gerner RH (1983) Eating disorders and antidepressants. J Clin Psychopharmacol 3:60Google Scholar
  49. Shader RJ, Greenblatt DJ (1982) The psychiatrist as mind sweeper. J Clin Psychopharmacol 2:233PubMedGoogle Scholar
  50. Stewart JW, Walsh BT, Wright L, Roose SP, Glassman AH (1984) An open trial of MAO-inhibitors in bulimia. J Clin Psychiatry 45:217PubMedGoogle Scholar
  51. Walsh BT, Gladis M, Roose SP, Stewart JW, Stetner F, Glassman AH (1988) Phenelzine vs. placebo in 50 patients with bulimia. Arch Gen Psychiatry 45:471PubMedGoogle Scholar
  52. Walsh BT, Stewart JW, Roose SP, Gladis M, Glassman AH (1984) Treatment of bulimia with phenelzine: A double-blind, placebo-controlled study. Arch Gen Psychiatry 41:1105PubMedGoogle Scholar
  53. Walsh BT, Stewart JW, Wright L, Harrison W, Roose SP, Glassman AG (1982) Treatment of bulimia with monoamine oxidase inhibitors. Am J Psychiatry 139:1629PubMedGoogle Scholar
  54. Wermuth BM, Davis KL, Hollister LE, Stunkard AJ (1977) Phenytoin treatment of the binge-eating syndrome. Am J Psychiatry 134:1249PubMedGoogle Scholar
  55. Wold P (1983) Trazodone in the treatment of bulimia (Letter). J Clin Psychiatry 44:275PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • M. M. Fichter

There are no affiliations available

Personalised recommendations