Influence of Blood Transfusions and Immunosuppressive Therapy on Malignancies in Renal Transplant Recipients
The Collaborative Transplant Study (CTS) was initiated in 1982, and 275 transplant centers are participating in the study. The data base of the information system currently contains information on more than 80000 kidney transplants. The analysis of malignancies for the period from 1982 through to 1988 included 610 malignancies in 61204 renal transplant recipients (RTR). Patients on the CTS register have a higher occurrence of malignancies of the urinary tract, lymphomas and Kaposi’s sarcoma than the normal population. At the time of the analysis, female RTR had a lower occurrence of breast cancer than the normal female population.
KeywordsBlood Transfusion Skin Cancer Renal Transplant Recipient Transplant Proc Renal Transplant Patient
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- Brooks JJ (1986) Kaposis sarcoma — a reversible hyperplasia. Lancet 2:1306Google Scholar
- Lopatin WB, Hickey DP, Nalesnik MA, Vivas CA, Flack C, Jordan ML, Starzl TE, Hakala TE (1990) Post-transplant lymphoproliferative disease and triple therapy. Clin Transplant 4:47–50Google Scholar
- Muir C, Waterhouse J, Mack T, Powell J, Whelan S (1987) Cancer incidence in five continents, vol 5. IARC Sci Publ 88 IARC, Lyons, pp 26–939Google Scholar
- Penn I (1988) Cancer after cyclosporine therapy. Transplantation Proc 20(1) 276–279Google Scholar
- West JC, Kelley SE, Pezzi CM (1986) Cyclosporine-induced lymphomas: controversies in diagnosis and treatment. Transplant Proc 18:1450–1454Google Scholar
- Zeller WJ, Scholler P, Roessler W, Lenhard V, Dreikorn K, Weber E, Schmähl D (1986) Allogenic blood transfusion and experimental tumor growth. Transplant Proc 18:1448–1449Google Scholar