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Screening of Lymphatic Tissues for the Presence of Human Herpesvirus 6 DNA Using the Polymerase Chain Reaction (PCR)

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PCR Topics

Abstract

A new human herpes-virus (HHV-6) was isolated recently from cultures of peripheral blood mononuclear cells derived from patients with lymphoproliferative disorders [1]. HHV-6 shows the characteristic structural and morphological features of an herpes-virus, but differs in nucleotide sequence and antigenic properties from other human herpesviruses. Infection with HHV-6 is widespread in the population. The virus appears to be the causative agent of exanthem subitum, a common childhood disease [2]. Moreover the virus is suspected to be involved in lymphatic disorders [3,4]. With the highly sensitive technique of the polymerase chain reaction (PCR) we examined different lymphatic biopsies for the detection of viral HHV-6 DNA.

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References

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© 1991 Springer-Verlag Berlin Heidelberg

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Ellinger, K., Neipel, F., Fleckenstein, B., Borisch-Chappius, B., Seidel, S., Mueller-Hermelink, K. (1991). Screening of Lymphatic Tissues for the Presence of Human Herpesvirus 6 DNA Using the Polymerase Chain Reaction (PCR). In: Rolfs, A., Schumacher, H.C., Marx, P. (eds) PCR Topics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75924-6_28

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  • DOI: https://doi.org/10.1007/978-3-642-75924-6_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52934-7

  • Online ISBN: 978-3-642-75924-6

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