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Molekulargenetische Untersuchungen beim yon Willebrand-Syndrom

  • Conference paper
20. Hämophilie-Symposion Hamburg 1989

  • 21 Accesses

Zusammenfassung

Der von Willebrand-Faktor ist ein multimeres Glykoprotein, welches in der Hämostase zwei wichtige Funktionen erfüllt. Einerseits wird er zur Anlagerung der Plättchen an geschädigtes Endothel benötigt, andererseits bindet er sich an Gerinnungsfaktor VIII und stabilisiert diesen in der Zirkulation [1, 2]. Die Rezeptoren des von Willebrand-Faktors an der Plättchenoberfläche sind bekannt — es handelt sich dabei um die Plättchenglykoproteine Ib und IIb/IIIa [3, 4].

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Author information

Authors and Affiliations

  1. Wien, Germany

    C. Mannhalter, S. Parzer & P. A. Kyrle

Authors
  1. C. Mannhalter
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  2. S. Parzer
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  3. P. A. Kyrle
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Editor information

Editors and Affiliations

  1. Abt. Hämatologie und Onkologie, Universitäts-Kinderklinik, Martinistraße 52, D-2000, Hamburg 20, Deutschland

    G. Landbeck

  2. Osterwaldstr. 16, D-8000, München 40, Deutschland

    R. Marx

  3. Zentrum der Inneren Medizin, Abt. für Angiologie, Universitätsklinikum, Theodor-Stern-Kai 7, D-6000, Deutschland

    I. Scharrer

  4. Hämostaseologische Abt., Med. Klinik Innenstadt der Univ., Ziemssenstr. 1 a, D-8000, München 2, Deutschland

    W. Schramm

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© 1990 Springer-Verlag Berlin Heidelberg

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Mannhalter, C., Parzer, S., Kyrle, P.A. (1990). Molekulargenetische Untersuchungen beim yon Willebrand-Syndrom. In: Landbeck, G., Marx, R., Scharrer, I., Schramm, W. (eds) 20. Hämophilie-Symposion Hamburg 1989. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75923-9_24

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  • DOI: https://doi.org/10.1007/978-3-642-75923-9_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52929-3

  • Online ISBN: 978-3-642-75923-9

  • eBook Packages: Springer Book Archive

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