Immunologische Bedeutung humaner Keratinozyten

  • J. Hunyadi
  • M. SimonJr.
  • A. Dobozy


In den letzten Jahren sind bezüglich der immunologischen Eigenschaften humaner Keratinozyten viele neue Erkenntnisse ermittelt worden, die diese Zellen heute in neuem Licht als aktive Immunzellen erscheinen lassen. Im folgenden wird über Oberflächenmarkereigenschaften, Zytokin- und Lipid-Mediatoren-Produktion humaner Keratinozyten sowie ihre funktionelle Bedeutung aus immunologischer Sicht ein aktueller Überblick gegeben.


Experimental data of the last few years concerning various immunological properties of human keratinocytes strongly suggest an immunocyte nature of these cells. This review. summarizes from the immunological point of view different surface markers, cytokine and arachidonic acid derivative production of human keratinocytes, with special reference to their functional significance.


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© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • J. Hunyadi
    • 1
  • M. SimonJr.
    • 1
    • 2
  • A. Dobozy
    • 1
  1. 1.Dermatologische Klinik der Szent-Györgyi Albert Medizinischen UniversitätSzegedDeutschland
  2. 2.Dermatologische Univ.-Klinik der Universität Erlangen-NürnbergErlangenDeutschland

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