Bone Union in Allografts: Chemotherapy Considerations
After conservative surgery for bone sarcomas, reconstructive procedures can use massive prostheses or bank allografts. Both have their own advantages and drawbacks. Massive stainless steel prostheses permit immediate weight bearing but do not permit reliable muscle reattachment and are threatened by secondary failures (progressive bone resorption, loosening, stem fracture). Bone bank allografts permit muscle reattachment and usually give better functional results and long-term tolerance but are threatened by fracture, infection, and non-union,especially when chemotherapy is used. This report tries to evaluate the risk of delayed union and nonunion of bone bank allografts when chemotherapy is used.
KeywordsTitanium Sarcoma Doxorubicin Methotrexate Cyclophosphamide
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