Pathophysiology and Pharmacology of Aspirin-Induced Asthma

  • A. Szczeklik
  • C. Virchow
  • M. Schmitz-Schumann
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 98)


Soon after its introduction into therapy in 1899, aspirin became an extremely successful analgesic and anti-inflammatory agent. Recently, its clinical applications have increased dramatically and include coronary artery disease and several related cardiovascular disorders. In patients with unstable angina or transient ischemic attacks aspirin favourably affects the course of disease, probably through its anti-platelet action (Reilly and Fitzgerald 1988). In acute myocardial infarction it significantly lowers mortality (isis-2 Collaborative Group 1988). Indeed, aspirin is now recognized as the most popular drug in the world.


Allergy Clin Immunol Sodium Cromoglycate Sodium Salicylate Tiaprofenic Acid Aspirin Intolerance 
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© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • A. Szczeklik
  • C. Virchow
  • M. Schmitz-Schumann

There are no affiliations available

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