Abstract
Of the histamine assays which are still in use, the fluorometric procedures are the second oldest type. Bioassays date back to when histamine was discovered in nature (Guggenheim and Löffler 1916), and fluorometric methods were developed more than 40 years later (Shore et al. 1959). By far the most biochemical studies with histamine in tissues, body fluids and isolated cells have been conducted with these techniques - this subchapter is a spin-off of a meta-analysis which had more than 45 000 reprints as the primary data base (Neugebauer et al. 1987).
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References
Anton AH, Sayre DF (1969) A modified fluorometric procedure for tissue histamine and its distribution in various animals. J Pharmacol Exp Ther 166:285–292
Atack C, Magnusson T (1978) A procedure for the isolation of noradrenaline (together with adrenaline), dopamine, 5-hydroxytryptamine and histamine from the same tissue sample using a single column of strongly acidic cation exchange resin. Acta Pharmacol Toxicol (Copenh) 42:35–57
Barth H, Crombach M, Schunack W, Lorenz W (1980) Evidence for a less high acceptor substrate specificity of gastric histamine methyltransferase: methylation of imidazole compounds. Biochem Pharmacol 29:1399–1407
Beaven MA, WoldeMussie E (1984) Histamine in body fluids: its measurement in different clinical states. New Engl Reg Allergy Proc 5:300–310
Bryant DH (1979) Concentration of histamine in the sputum of patients with asthma or chronic bronchitis. In: Pepys J, Edwards AM (eds) The mast cell-its role in health and disease. International Symposium, Davos. Pitman, Bath, pp 309–314
Burkhalter A (1962) The formation of histamine by fetal rat liver. Biochem Pharmacol 11:315–322
Büttner J, Borth R, Bontwell HJ, Broughton PMG, Bowyer RC (1980) Approved recommendation (1978) on quality control in clinical chemistry. II. Assessment of analytical methods for routine use. J Clin Chem Clin Biochem 18:78–88
Carlini EA, Green JP (1963) The measurement of histamine in brain and its distribution. Biochem Pharmacol 14:1448–1449
Ennis M, Lorenz W, Kapp B, Lüben L, Schmal A (1985) Comparison of the histaminereleasing activity of cremophor El and some of its derivatives in two experimental models: the in vivo anaesthetized dog and in vitro rat peritoneal mast cells. Agents Actions 165:265–267
Feinstein AR (1975) Clinical biostatistics. XXXI. On the sensitivity, specificity and discrimination of diagnostic tests. Clin Pharmacol Ther 17:104–116
Galen RS, Gambino SR (1975) Beyond normality: the predictive value and efficiency of medical diagnoses. Wiley, New York, pp 1–237
Gleich GJ, Hull WM (1980) Measurement of histamine: a quality control study. J Allergy Clin Immunol 66:295–298
Graham H, Scarpellini JAD, Hubka BP, Lowry OH (1968) Measurement and normal range of free histamine in human blood plasma. Biochem Pharmacol 17: 2271–2280
Green H, Erickson, RW (1967a) Effect of some drugs upon the histamine concentration of guinea pig brain. Arch Int Pharmacodyn 166:121–126
Green H, Erickson RW (1967b) Effect of some drugs upon the histamine concentration of rat heart. Arch Int Pharmacodyn 166:127–135
Guggenheim M, Löffler W (1916) Biologischer Nachweis proteinogener Amine in Organextrakten und Körperflüssigkeiten. Biochem Z 72:303–324
Habbema JDF, Hilden J, Bjerregaard B (1978) The measurement of performance in probabilistic diagnosis. I. The problem descriptive tools and measures based on classification matrices. Meth Inform Med 17:217–226
Habbema JDF, Hilden J, Bjerregaard B (1981) The measurement of performance in probabilistic diagnosis. V. General recommendations. Methods Inf Med 20: 97–100
Häkanson R, Rönnberg AL (1974) Improved fluorometric assay of histamine: condensation with o-phthaldialdehyde at -20°C. Anal Biochem 60:560–567
Häkanson R, Juhlin C, Owman C, Sporrong B (1970) Histochemistry of histamine: microspectrofluorometric characterization of the fluorophores induced by o-phthaldialdehyde. J Histochem Cytochem 18:93–99
Häkanson R, Rönnberg AL, Sjölund K (1972) Fluorometric determination of histamine with OPT: optimum reaction conditions and tests of identity. Anal Biochem 47:356–370
Healy MJR, Mitchell FL (1974) Quality control and normal values. In: Curtius HC, Roth M (eds) Clinical biochemistry, principles and methods, de Gruyter, Berlin, pp 594–617
Hesterberg R, Sattler J, Lorenz W, Stahlknecht C-D, Barth H, Crombach M, Weber D (1984) Histamine content, diamine oxidase activity and histamine methyltrans-ferase activity in human tissues: facts or fictions? Agents Actions 14:325–334
Kownatzki E, Grünninger G, Fuhr N (1987) Interference with the fluorometric histamine assay by biogenic amines and amino acids. Pharmacology 23:17–24
Kremzner LT, Pfeiffer CC (1966) Identification of substances interfering with the fluorometric determination of brain histamine. Biochem Pharmacol 15:197–200.
Kremzner LT, Wilson JB (1961) A procedure for the determination of histamine. Biochim Biophys Acta 50:364–367
Kurahashi K, Fujiwara Μ (1969) Fluorometric assay of tissue histamine. Jpn J Pharmacol 19:240–248
Kusche J, Lorenz W (1971) A new method for concomitant determination of l -histidine and histamine in tissues and body fluids. Naunyn Schmiedebergs Arch Pharmacol [Suppl] 270:R 90
Kusche J, Lorenz W, Stahlknecht CD, Richter H, Hesterberg R, Schmal A, Hinterlang E, Weber D, Ohmann C (1981) Intestinal diamine oxidase and histamine release in rabbit mesenteric ischemia. Gastroenterology 80:980–987
Levey S, Jennings ER (1950) The use of control charts in the clinical laboratory. Am J Clin Pathol 20:1059–1066
Lewis SJ, Fennessy MR (1981) Fluorometric determination of peripheral tissue histamine levels using Bio-Rex 70. Agents Actions 11:228–236
Lieber ER, Taylor SL (1978) Comparison of thin-layer chromatographic detection methods for histamine from food extracts. J Chromatogr 160:227–237
Lorenz W, Doenicke A (1978a) Anaphylactoid reactions and histamine release by intravenous drugs used in surgery and anaesthesia. In: Watkins J, Ward AM (eds) Adverse response ro intravenous drugs. Academic, London; Grune and Stratton, New Yprk, pp 83–112
Lorenz W, Doenicke A (1978b) Histamine release in clinical conditions. M Sinai J Med (NY) 45:357–386
Lorenz W, Haibach S, Gerant M, Werle E (1969) Specific histidine decarboxylases in the gastric mucosa of man and other mammals: determination, location and properties. Biochem Pharmacol 18:2625–2637
Lorenz W, Benesch L, Barth H, Matejka E, Meyer R, Kusche J, Hutzel M, Werle E (1970) Fluorometric assay of histamine in tissues and body fluids: choice of the purification procedure and identification in the nanogram range. Z Anal Chem 252:94–98
Lorenz W, Barth H, Kusche J, Reimann J-J, Schmal A, Matejka A, Mathias C, Hutzel M, Werle E (1971) Histamine in the pig: determination, distribution, release and pharmacological actions. Eur J Pharmacol 14:155–175
Lorenz W, Reimann H-J, Barth H, Kusche K, Meyer R, Doenicke A, Hutzel M (1972) A sensitive and specific method for the determination of histamine in human whole blood and plasma. Hoppe Seylers Z Physiol Chem 353:911–920
Lorenz W, Matejka E, Schmal A, Seidel W, Reimann H-J, Uhlig R, Mann G (1973a) A phylogenetic study on the occurrence and distribution of histamine in the gastro-intestinal tract and other tissues of man and various animals. Comp Gen Pharmacol 4:229–250
Lorenz W, Hundt A, Kusche J, Barth H, Haubensack G, Hutzel M, Schmal A, Gerant M, Wächter A, Matejka E, Hahn H, Werle E (1973b) Histamine and salivary secretion. In: Maslinski (ed) Histamine. Dowden, Hutchinson and Ross, Philadelphia, pp 187–199
Lorenz W, Barth H, Thermann M, Schmal A, Dormann P, Niemeyer I (1974a) Fluorometric histamine determination of canine plasma under normal conditions, following application of exogenous histamine, and during histamine release by Haemaccel. Hoppe Seylers Z Physiol Chem 355:1097–1111
Lorenz W, Thermann M, Messmer K, Schmal A, Dormann P, Kusche J, Barth H, Tauber R, Hutzel M, Mann G, Uhlig R (1974b) Evaluation of histamine elimination curves in plasma and whole blood of several circulatory regions: a method for studying kinetics of histamine release in the whole animal. Agents Actions 4:336–356
Lorenz W, Barth H, Karges HE, Schmal A, Dormann P, Niemeyer I (1974c) Problems in the assay of histamine release by gelatin: o -phthaldialdehyde-induced fluorescence, inhibition of histamine methyltransferase and H1-receptor antagonism by Haemaccel. Agents Actions 4:324–335
Lorenz W, Seidel W, Doenicke A, Tauber R, Reimann H-J, Uhlig R, Mann G, Dormann P, Schmal A, Häfner G, Hamelmann H (1974d) Elevated plasma histamine concentrations in surgery: causes and clinical significance. Klin Wochenschr 52:419–425
Lorenz W, Troidl H, Barth H, Rohde H (1978) Histamine, gastric secretion and peptic ulcer disease: an attempt to define special sources of error and problems in clinical-biochemical trials. In: Creutzfeldt W (ed) Proceedings of an international symposium on histamine: H2-receptor antagonists. Excerpta Medica, Amsterdam, pp 6–36
Lorenz W, Parkin JV, Rohde H, Barth H, Troidl H, Thon K, Hinterlang E, Weber D, Albrecht R, Röher D (1981a) Histamine in gastric secretory disorders: the relevance of the mucosal histamine content and the origin of histamine in gastric aspirate. In: Konturek SJ, Domschke W (eds) Gastric secretion basic and clinical aspects. Thieme, Stuttgart, pp 29–52
Lorenz W, Doenicke A, Schöning B, Neugebauer E (1981b) The role of histamine in adverse reactions to intravenous agents. In: Thornton (ed) Adverse reactions to anaesthetic drugs. Elsevier/North-Holland, Amsterdam, pp 169–238
Lorenz W, Neugebauer E, Schmal A (1982a) Le dosage de l’histamine plasmatique lors de réactions anaphylactoides chez le sujet anèsthésié. Influence des méthodes de prélèvement et de la préparation du plasma sur l’histaminémie mesurée. Ann Fr Anesth Reanim 1:271–276
Lorenz W, Doenicke A, Schöning B, Ohmann C, Grote B, Neugebauer E (1982b) Definition and classification of the histamine-release response to drugs in anaesthesia and surgery: studies in the conscious human subject. Klin Wochenschr 60:896–913
Lorenz W, Schmal A, Neugebauer E, Doenicke A, Schöning B, Rohner H (1985) Histaminbestimmungsmethoden. In: Doenicke A, Lorenz W (eds) Histamin und Histamin-Rezeptor-Antagonisten. Springer, Berlin Heidelberg New York, pp 67–83
Lorenz W, Thon K, Neugebauer E, Stöltzing H, Ohmann C, Weber D, Schmal A, Hinterlang E, Barth H, Kusche J (1987a) Reliability and practicability of the fluorometric-fluoroenzymatic histamine determination in pathogenetic studies on peptic ulcer: detection limits and problems with specificity. Agents Actions 21:1–25
Lorenz W, Thon K, Lindlar R, Stöltzing H, Weber D, Ohmann C (1987b) Chemical-analytical bias in cohort studies with controls on the pathogenesis of peptic ulcer: detection by cusum control charts. Hepatogastroenterology 34:40–41
Lorenz W, Doenicke A, Dietz W (1987c) Release of histamine by H2-receptor antagonists. Lancet 2:1098–1098
Medina M, Shore PA (1966) Increased sensitivity in a specific fluorometric method for brain histamine. Biochem Pharmacol 15:1627–1629
Michaelson JA, Coffman PZ (1967) Histamine and spermidine in tissues of the guinea pig. Biochem Pharmacol 19:1636–1641
Michaelson JA, Coffman PZ (1969) An improved ion-exchange purification procedure for the fluorometric assay of histamine. Anal Biochem 27:257–261
Myers G, Donlon M, Kaliner M (1981) Measurement of urinary histamine: development of methodology and normal values. J Allergy Clin Immunol 67:305–311
Nakamura H (1977) Thin-layer chromatography of histidine, histamine and histidyl peptides at picomole level using a unique fluorogenic reaction with fluorescamine. J Chromatogr 131:215–222
Neugebauer E (1978) Fluorometric determination of histamine in human plasma: improvements of the present techniques in the pmol-range and development of a new procedure with high sensitivity, specificity and precision in the femtomole range. Diploma thesis, University of Marburg
Neugebauer E, Lorenz W (1981) Histamine in health and disease. Behring Inst Mitt 68:102–133
Neugebauer E, Lorenz W, Maroske D, Barthlen W, Ennis M (1987) The role of mediators in septic/endotoxic shock. A metaanalysis evaluating the current status of histamine. Theor Surg 2:1–28
Parkin JV, Lorenz W, Barth H, Rohde H, Ohmann C, Thon K, Weber D, Crombach M (1982) Assay and identification of histamine in human gastric aspirate by a fluorometric-fluoroenzymatic technique. Its application in patients with chronic duodenal ulcer. Agents Actions 12:17–25
Rohde H, Lorenz W, Troidl H, Reimann H-J, Häfner G, Weber D (1980) Histamine and peptic ulcer: influence of sample-taking on the precision and accuracy of fluorometric histamine assay in biopsies of human gastric mucosa. Agents Actions 10:175–185
Rönnberg AL (1983) O-Phthaldialdehyde as a fluorogenic reagent for various biogenic compounds with special reference to histamine. Thesis, University of Lund, pp 6–32
Rönnberg AL, Häkanson R (1984) A simplified procedure for the fluorometric determination of histamine in rat stomach. Agents Actions 14:195–199
Rönnberg AL, Hansson C, Hakanson R (1984) High-performance liquid chromatographic determination of histamine in biological samples after derivation with o-phthaldialdehyde. Anal Biochem 139:338–344
Sattler J, Häfner D, Klotter H-J, Lorenz W, Wagner PK (1988) Food-induced hista-minosis as an epidemiological problem: plasma histamine elevation and haemo-dynamic alterations after oral histamine administration and blockade of diamine oxidase (DAO). Agents Actions 23:361–365
Schippert B, Kovar KA, Sweing K-F (1979) Determination of histamine and its metabolic products in the pig gastric mucosa. Pharmacology 19:86–95
Shore PA, Burkhalter A, Cohn VH Jr (1959) A method for the fluorometric assay of histamine in tissues. J Pharmacol Exp Ther 127:182–186
Stamm D (1988) Qualitätssicherung der quantitativen Bestimmungen im Laboratorium. Neue Richtlinien der Bundesärztekammer. Mitt Dtsch Ges Klin Chem 3:133–162
Subramanian N, Schinzel W, Mitznegg P, Estler C-J (1978) Regional levels of histamine in rat brain after microwave irradiation. Evidence for artefacts in the enzymatic isotopic assay. Agents Actions 8:488–490
Thon KP (1983) Klinische Relevanz and Zuverlässigkeit der Bestimmung von Histamin im oberen Verdauungstrakt beim chronischen Ulcus duodeni und nach selektiver-proximoler Vagotomie. Habilitation thesis, University of Marburg
Thon KP, Lorenz W, Ohmann C, Weber D, Rohde H, Röher HD (1985) Sample taking problems in measuring actual histamine levels of human gastroduodenal mucosa: specific and general relevance in clinical trials on peptic ulcer pathogenesis and selective proximal vagotomy. Gut 26: 1165–1178
Thunberg R (1967) Localization of cells containing and forming histamine in the gastric mucosa of the rat. Exp Cell Res 47:108–115
Uldall A (1987) Quality assurance in clinical chemistry. Scand J Clin Lab Invest 47: 1–95
Von Redlich D, Glick D (1965) Studies in histochemistry. LXXVI. Fluorometric determination of histamine in microgram samples of tissue or microliter volumes of body fluids. Anal Biochem 10:459–467
Von Redlich D, Glick D (1969) Improvements in fluorometric microdeterminations of histamine and serotonin. Anal Biochem 29:167–171
Yamatodani A, Watanabe T, Wada H (1983) Methods for determination of histamine in biological materials. In: Parvez S, Nagatsu T, Nagatsu I, Parvez H (eds) Methods in biogenic amine research. Elsevier, Amsterdam, pp 663–687
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Lorenz, W., Neugebauer, E. (1991). Fluorometric Assays. In: Uvnäs, B. (eds) Histamine and Histamine Antagonists. Handbook of Experimental Pharmacology, vol 97. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75840-9_3
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DOI: https://doi.org/10.1007/978-3-642-75840-9_3
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