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Fluorometric Assays

  • Chapter
Histamine and Histamine Antagonists

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 97))

Abstract

Of the histamine assays which are still in use, the fluorometric procedures are the second oldest type. Bioassays date back to when histamine was discovered in nature (Guggenheim and Löffler 1916), and fluorometric methods were developed more than 40 years later (Shore et al. 1959). By far the most biochemical studies with histamine in tissues, body fluids and isolated cells have been conducted with these techniques - this subchapter is a spin-off of a meta-analysis which had more than 45 000 reprints as the primary data base (Neugebauer et al. 1987).

Supported by a grant from the Deutsche Forschungsgemeinschaft (LO 199/14-4 and LO 199/16-1).

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Authors
  1. W. Lorenz
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  2. E. Neugebauer
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Editors and Affiliations

  1. Department of Pharmacology, Karolinska Institutet, Box 60400, S-104 01, Stockholm, Sweden

    Börje Uvnäs M.D.

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© 1991 Springer-Verlag Berlin Heidelberg

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Lorenz, W., Neugebauer, E. (1991). Fluorometric Assays. In: Uvnäs, B. (eds) Histamine and Histamine Antagonists. Handbook of Experimental Pharmacology, vol 97. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75840-9_3

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  • DOI: https://doi.org/10.1007/978-3-642-75840-9_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75842-3

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