Abstract
Since the first issue on histamine in the Handbook of Pharmacology (Rocha E Silva 1966), in which only eight pages were devoted to brain histamine (White 1966), great progress has been made in this field. Pioneering neurochemical studies by Schwartz and his colleagues (see Scheartz et al. 1986a) were corroborated and refined in detail by immunohistochemical demonstration of the histaminergic neurone system in rat brain (Watanabe et al. 1984; Panula et al. 1984; Steinbusch and Mulder 1984). Now there is convincing evidence that histamine is a neurotransmitter or a neuromodulator in the mammalian brain.
Keywords
- Intracerebroventricular Injection
- Histidine Decarboxylase
- Histaminergic Neurone
- Histaminergic System
- Endogenous Histamine
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Yamatodani, A., Inagaki, N., Panula, P., Itowi, N., Watanabe, T., Wada, H. (1991). Structure and Functions of the Histaminergic Neurone System. In: Uvnäs, B. (eds) Histamine and Histamine Antagonists. Handbook of Experimental Pharmacology, vol 97. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75840-9_16
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