Estrogen Regulation of mRNAs in the Brain and Relationship to Lordosis Behavior

  • A. H. Lauber
  • D. Pfaff
Part of the Current Topics in Neuroendocrinology book series (CT NEUROENDOCRI, volume 10)


Hormone-driven reproductive behaviors appear to offer interesting opportunities to relate detailed molecular brain mechanisms to specific vertebrate behavioral responses. Gonadal steroid hormones have a major role in the regulation of behavior (Beach 1981). Sexual, aggressive, social, locomotor, and consumptory behaviors are influenced and in some cases controlled by the actions of gonadal steroids on the brain. In many instances, behavior is as reliable a marker for hormone efficacy as any molecular substrate. Moreover, behavioral assays provide suggestions about the physiological ramifications of molecular events occurring in vivo. Some of the best understood systems are the steroid hormone-dependent sexual behaviors exhibited by female rats and other rodents. These behaviors require estrogen and progesterone and are driven by the receptor-mediated genomic effects of the hormones.


Estradiol Benzoate Progestin Receptor Hormone Response Element Estrogen Regulation Female Sexual Behavior 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • A. H. Lauber
  • D. Pfaff
    • 1
  1. 1.Laboratory of Neurobiology and BehaviorThe Rockefeller UniversityNew YorkUSA

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