Abstract
Corticotropin-releasing factor (CRF) is a 41 amino acid peptide with potent activating effects on the pituitary adrenal axis, as shown by its ability to release adrenocorticotropin hormone and β-endorphin from the anterior pituitary (Vale et al. 1981). In accordance with such a role, a large proportion of central nervous system CRF is located within the hypothalamus (Bloom et al. 1982).
This research was supported by grant number AM26741 from the National Institute of Diabetes and Digestive and Kidney Diseases.
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Baldwin, H.A., Britton, K.T., Koob, G.F. (1990). Behavioral Effects of Corticotropin-Releasing Factor. In: Ganten, D., Pfaff, D. (eds) Behavioral Aspects of Neuroendocrinology. Current Topics in Neuroendocrinology, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75837-9_1
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