Transdermal Administration of Nitrates
Nitrates are given transdermally to avoid first-pass hepatic metabolism and to achieve constantly high plasma concentrations. The most widely used method is transdermal nitroglycerin patches (discs). Nitroglycerin and ISDN ointments are also available.
KeywordsPulmonary Capillary Wedge Pressure Chronic Congestive Heart Failure Sublingual Nitroglycerin Silent Ischemia Intermittent Therapy
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