Zusammenfassung
Ein maligner Primärtumor ist inkurabel, wenn er nicht entfernt oder seine Entfernung wegen der damit verbundenen Folgen nicht hingenommen werden kann und wenn es keine kurativ wirksame konservative Behandlung gibt. Die nichtchirurgische kurative Behandlung ist bis heute als alleinige Maßnahme nur bei wenigen Organtumoren möglich, so daß sich das Schicksal des Kranken meistens mit der Frage nach der chirurgischen Kurabilität entscheidet. Es lag nahe zu versuchen, durch möglichst weitgehende Radikalität des Eingriffs die Grenzen auszudehnen. Dieses Konzept hat für viele Tumoren enttäuscht und ist zum Teil wieder verlassen (z. B. Pankreaskarzinom, Rektumkarzinom, nach unserer Meinung Ösophaguskarzinom, gynäkologische Karzinome u. a.). Für verschiedene Geschwülste wurden kombinierte Schemata der primären Behandlung (Operation, Bestrahlung, Chemotherapie, Immuntherapie) entwickelt und dabei eine weniger radikale und weniger verstümmelnde Operation als Teil eingefügt (z. B. Analkarzinom, Extremitätensarkome, verschiedene kindliche Malignome wie Neuroblastome oder Wilms-Tumore, differenzierte Schilddrüsenkarzinome u.a.).
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Pichlmaier, H. et al. (1991). Medizinische Behandlungsmaßnahmen. In: Pichlmaier, H., Müller, J.M., Jonen-Thielemann, I. (eds) Palliative Krebstherapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75783-9_4
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