Malignome des Dünn- und Dickdarms

  • J. M. Müller
  • W. Holzmüller

Zusammenfassung

Nur 1% aller gastrointestinal en Malignome entsteht im Dünndarm. Adenokarzinome bilden, gefolgt von den Karzinoiden, das großte Kontingent (Tabelle 1). Der Anteil der Sarkome, deren Ursprung meist die glatte Muskulatur, selten das Fettgewebe bzw. eine neurale oder vaskuäre Struktur ist, beträgt um 20% und der der malignen Lymphome etwa 1%.

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Literatur

  1. 1.
    Barclay THC, Schapira DV (1983) Malignant tumors of the small intestine. Cancer 51: 878–881PubMedCrossRefGoogle Scholar
  2. 2.
    Buchholz J, Strosche H, Krawzak HW, Kahl N (1988) Primäre Dünndarmmalignome - Symptomatik, Diagnostik und Therapie. Leber Magen Darm 4: 197–203Google Scholar
  3. 3.
    Coutsoftides T, MacDonald J, Shibata JHR (1977) Carcinoma of the pancreas and periampullary region: A 41 year experience. Ann Surg 186: 730–733PubMedCrossRefGoogle Scholar
  4. 4.
    Herbsman H, Wetstein L, Rosen Y (1980) Tumors of the small intestine. CUff Probl Surg 17: 122–184Google Scholar
  5. 5.
    Lai ECS, Doty JE, Irving C, Tompkins RK (1988) Primary adenocarcinoma of the duodenum: Analysis of survival. World J Surg 12: 695–699PubMedCrossRefGoogle Scholar
  6. 6.
    Loehr WJ, Mujahed Z, Zahn FD (1969) Primary lymphoma of the gastrointestinal tract: A review of 100 cases. Ann Surg 170: 232–238PubMedCrossRefGoogle Scholar
  7. 7.
    Müller G, Geisbe H (1978) Bösartige Tumoren des Dünndarms. Zentralbl Chir 103: 911–917PubMedGoogle Scholar
  8. 8.
    Nakase A, Matsumoto Y, Uchida K (1977) Surgical treatment of cancer of the pancreas and the periampullary region: Cumulative results in 57 institutions in Japan. Ann Surg 185: 52–57PubMedCrossRefGoogle Scholar
  9. 9.
    Pagtalunan RJG, Mayo CW, Dockerty MB (1964) Primary malignant tumors of the small iritestine. Am J Surg 108: 13–18PubMedCrossRefGoogle Scholar
  10. 10.
    Rosenberg SA, Sindelar WF (1980) Surgery and adjuvant radiation-chemo-immunotherapy in soft tissue sarcomas. Result of treatment at the National Cancer Institute. In: van Oosterom AT, Muggia FM, Cleton FJ (eds) Therapeutic progress in ovarian cancer, testicular cancer and the sarcomas. Boston, pp 397–412CrossRefGoogle Scholar
  11. 11.
    Schmoll HJ, Peters H-D, Fink U (1987) Kompendium intemistische Onkologie. Springer, Berlin Heidelberg New York TokyoGoogle Scholar
  12. 12.
    Shukla SK, Elias EG (1976) Primary neoplasms of the duodenum. Surg Gynecol Obstet 142: 858–860PubMedGoogle Scholar
  13. 13.
    Tonak J, Hohenberger W, Kockerling F (1988) Leistungen der Tumorchirurgie bei Tumoren des Dunndarmes. Langenbecks Arch Chir [Suppl II] (Kongreßbericht), S 283Google Scholar
  14. 14.
    UICC (1987) TNM-Klassifikation maligner Tumoren. Springer, Berlin Heidelberg New York TokyoGoogle Scholar
  15. 15.
    Warren KW, Choe DS, Plaza J (1975) Results of radical resection forperiampullary cancer. Ann Surg 181: 534–540PubMedCrossRefGoogle Scholar
  16. 16.
    Williamson RCN, Welch CE, Malt RA (1983) Adenocarcinoma and lymphoma of the small intestine. Ann Surg 197: 172–178PubMedCrossRefGoogle Scholar
  17. 17.
    Wilson JM, Melvin DB, Gray GF, Thorbjamarson B (1974) Primary malignancies of the small bowel: A report of 96 cases and review of the literature. Ann Surg 180: 175–179PubMedCrossRefGoogle Scholar
  18. 1.
    Becker N, Frentzel-Beyme R, Wagner G (1984) Krebssterblichkeit in Deutschland und Uindern der Bundesrepublik Deutschland. Krebsatlas der Bundesrepublik Deutschland 2.Aufl. Springer, Berlin Heidelberg New York TokyoGoogle Scholar
  19. 2.
    Bengmark S, Hafstrom L (1970) The natural history of primary and secondary malignant tumors of the liver: I. prognosis for patients with hepatic metastases from colonic and rectal carcinoma by laparotomy. Cancer 23: 198CrossRefGoogle Scholar
  20. 3.
    Bengtsson G, Carlsson G, Hafstrom L (1981) Natural history of patients with untreated liver metastases from colorectal cancer. Am J Surg 141: 586PubMedCrossRefGoogle Scholar
  21. 4.
    Boey J, Choi TK, Wong J, Ong G (1981) Carcinoma of the colon and rectum with liver involvement. Surg Gynecol Obstet 153: 864PubMedGoogle Scholar
  22. 5.
    Bown SG, Barr H, Matthewson K, Hawes R, Swain CP, Clark CG, Boulos PB (1986) Endoscopic treatment of inoperable colorectal cancers with the Nd YAG laser. Br J Surg 73: 949PubMedCrossRefGoogle Scholar
  23. 6.
    Brown PW, Terz JJ, Lawrence W, Blievernicht SW (1977) Survival after palliative surgery for advanced intraabdominal cancer. Am J Surg 134: 575PubMedCrossRefGoogle Scholar
  24. 7.
    Butler J, Attiyeh FF, Daly JM (1986) Hepatic resection for metastases of the colon and rectum. Surg Gynecol Obstet 162: 109PubMedGoogle Scholar
  25. 8.
    Buyse M, Zeleniuch-Jacquotte A, Chalmers TC (1988) Adjuvant therapy of colorectal cancer. JAM A 259: 3571CrossRefGoogle Scholar
  26. 9.
    Cabano F, Zechini F, Locatelli G, Verri C (1983) Le occlusion neoplastiche del grosso intestine. Chir Helv 35: 742Google Scholar
  27. 10.
    Cady B, Monson DO, Swinton NW (1970) Survival of patients after colonic resection for carcinoma with simultaneous liver metastases. Surg Gynecol Obstet 131: 697PubMedGoogle Scholar
  28. 11.
    Cahan WG, Castro EB, Hadju SI (1974) The significance of a solitary lung shadow in patients with colon carcinoma. Cancer 33: 414PubMedCrossRefGoogle Scholar
  29. 12.
    Cattell RB (1938) The factors influencing operability and mortality in carcinomas of the large bowel. Proc Interst Postgrad MA, North Am 91Google Scholar
  30. 13.
    Daland EM, Welch CE, Nathanson I (1936) One hundred unreated cancers of the rectum. N Engl J Med 214: 451CrossRefGoogle Scholar
  31. 14.
    Dionne RS (1965) The pattern of blood-borne metastasis from carcinoma of rectum. Cancer 18: 775PubMedCrossRefGoogle Scholar
  32. 15.
    Douglass HO (1987) Adjuvant treatment in colorectal cancer: An update. World J Surg 11: 478PubMedCrossRefGoogle Scholar
  33. 16.
    Dukes CE (1940) Cancer of the rectum. An analysis of 1000 cases. J Pathol Bacteriol 50: 527CrossRefGoogle Scholar
  34. 17.
    Eibl-Eibesfeldt B (1989) Regionale Chemotherapie von Lebermetastasen. Krankenhausarzt 62: 114Google Scholar
  35. 18.
    Evans JT, Vana J, Aronoff BL, Baker HW, Murphy GP (1978) Management and survival of carcinoma of the colon: Results of a national survey by the American College of Surgeons. Ann Surg 188: 716PubMedCrossRefGoogle Scholar
  36. 19.
    Gall FP, Tonak J, Altendorf A, Kuruz A (1985) Operationstaktik und Ergebnisse bei erweiterten Operationen colorectaler Carcinome. Langenbecks Arch Chir 366: 445PubMedCrossRefGoogle Scholar
  37. 20.
    Gennari L, Doci R, Bignami P (1986) Surgical treatment of hepatic metastases from colorectal cancer. Ann Surg 203: 49PubMedCrossRefGoogle Scholar
  38. 21.
    Hermanek P (1989) Aktuelle Aspekte der neuen Stadieneinteilung des colorectalen Karzinoms und ihre klinischen Konsequenzen. Chirurg 60: 1–7PubMedGoogle Scholar
  39. 22.
    Hohenberger W, Altendorf P, Hermanek P (1986) The laser in gastroenterology: Malignant tumors in the lower gastrointestinal tract - therapeutic alternatives. Endoscopy 18: 47–52PubMedCrossRefGoogle Scholar
  40. 23.
    Joffe J, Gordon PH (1981) Palliative resections for colorectal carcinoma. Dis Colon Rectum 24: 355PubMedCrossRefGoogle Scholar
  41. 24.
    Kennan S, Boustany C (1988) Surgical management of the acutely obstructed colon. Am J Surg 156: 163CrossRefGoogle Scholar
  42. 25.
    Kern KA, Pass HI, Roth JA (1987) Surgical treatment of pulmonary metastases. In: Rosenberg SA (ed) Surgical treatment of metastatic cancer. Lippincott, Philadelphia, p 69Google Scholar
  43. 26.
    Kiefhaber P, Huber F, Kiefhaber K (1987) Palliative and preoperative endoscopic neodymiumYAG laser, treatment of colorectal carcinoma. Endsocopy 19: 43CrossRefGoogle Scholar
  44. 27.
    Kiene S, Walter F (1987) Die operative Therapie bei tumorbedingtem Dickdarmileu. Zentralbl Chir 112: 337PubMedGoogle Scholar
  45. 28.
    Klempert A, Martyniuk V, Demin V (1986) Neotlozhnye operatsii psi oslozhnennykh formakh raha obodochnoi kishki. Vestn Khir 137: 38PubMedGoogle Scholar
  46. 29.
    Lahiri SR, Boileau G, Hall TC (1971) Treatment of metastatic carcinoma with 5-fluorouracil by mouth. Cancer 29: 902CrossRefGoogle Scholar
  47. 30.
    Leone BA, Romero A, Rabinovich MG, Perez JE (1986) Sequential therapy with methotrexate and 5-fluorouracil in the treatment of advanced colorectal carcinoma. J Clin Oncol 4: 23PubMedGoogle Scholar
  48. 31.
    Madajewicz S, Petrelli N, Rustum YM, Campbell J (1984) Phase I–II trial of high dose calcium leukovorin and 5-fluorouracil in advanced colorectal cancer. Cancer Res 44: 4667PubMedGoogle Scholar
  49. 32.
    Mathus-Vliegen EMH, Tytgat GNJ (1986) Laser ablation and palliation in colorectal malignancy. Gastrointest Endosc 32: 393PubMedCrossRefGoogle Scholar
  50. 33.
    McCormack PM, Attiyeh FF (1979) Resection of pulmonary metastases from colorectal cancer. Dis Colon Rectum 22: 553PubMedCrossRefGoogle Scholar
  51. 34.
    McCormack PM, Bains MS, Beattie JR (1978) Pulmonary resection in metastatic carcinoma. Chest 73: 163PubMedCrossRefGoogle Scholar
  52. 35.
    Modlin J, Walker H (1949) Palliative resections in cancer of the colon and rectum. Cancer 2, 767–776PubMedCrossRefGoogle Scholar
  53. 36.
    Morrow CE, Vassipoulos PP, Grage TB (1981) Surgical resection for metastatic neoplasms of the lung: Experiences at the University of Minnesota Hospitals. Cancer 45: 2981CrossRefGoogle Scholar
  54. 37.
    Mountain CF, Khalil KG, Hermes KE (1978) The contributions of surgery to the management of carcinomatous pulmonary metastases. Cancer 41: 833PubMedCrossRefGoogle Scholar
  55. 38.
    Mountain CF, McMurtrey MJ, Hermes KE (1984) Surgery for pulmonary metastases: A 20-year experience. Ann Thorac Surg 38: 323PubMedCrossRefGoogle Scholar
  56. 39.
    Nielsen J, Balslev I, Jensen HE (1971) Carcinoma of the colon with liver metastases. Acta Chir Scand 137: 463PubMedGoogle Scholar
  57. 40.
    Oxley EM, Ellis H (1969) Prognosis of carcinoma of the large bowel in the presence of liver metastases. Br J Surg 56: 149PubMedCrossRefGoogle Scholar
  58. 41.
    Pandya KJ, Chang A YC, Qazi R, Rubens J, Asburg R (1986) Combination chemotherapy for advanced colorectal cancer. Am J Clin Oncol 9: 31PubMedCrossRefGoogle Scholar
  59. 42.
    Petrelli HJ, Nambisan RN, Herrera L (1985) Hepatic resection for isolated metastasis from colorectal carcinoma. Am J Surg 149: 205PubMedCrossRefGoogle Scholar
  60. 43.
    Pichlmayr R, Bretschneider HJ, Kirchner E et al. (1988) Ex situ Operation an der Leber. Eine neue Möglichkeit in der Leberchirurgie. Langenbecks Arch Chir 373: 122PubMedCrossRefGoogle Scholar
  61. 44.
    Pickren JW, Tsukada Y, Lane WW (1982) Liver metastases: Analysis of autopsy data. In: Weiss L, Gilbert HA (eds) Liver metastases. Plenum, New YorkGoogle Scholar
  62. 45.
    Ravo B (1987) The intracolonic bypass procedure. Int J Colorect Dis 2: 38CrossRefGoogle Scholar
  63. 46.
    Registry of Hepatic Metastase (1988) Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of indications for resection. Surgery 103: 278Google Scholar
  64. 47.
    Russin OJ, Kaplan SR, Goldberg RI, Barkin JS (1986) Neodymium-YAG Laser. A new palliative tool in the treatment of colorectal cancer. Arch Surg 121: 1399PubMedCrossRefGoogle Scholar
  65. 48.
    Schildberg FW, Meyer G (1988) Palliative Operationsverfahren beim fortgeschrittenen CoIonkarzinom. Chirurg 59: 625PubMedGoogle Scholar
  66. 49.
    Schmidt CG (1983) Chemotherapie fortgeschrittener Tumoren des GastrointestinaItraktes. In: Eigler FW, Gross E (Hrsg) Ergebnisse der Chirurgischen Onkologie. Enke, StuttgartGoogle Scholar
  67. 50.
    Schmoll HJ, Peters HD, Fink V (1987) Kompendium intemistische Onkologie. Springer, Berlin Heidelberg New York TokyoGoogle Scholar
  68. 51.
    Seifert P, Baker LH, Rees ML, Vaitkevicius VK (1975) Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma. Cancer 36: 123PubMedCrossRefGoogle Scholar
  69. 52.
    Silvermann DT, Murray JL, Smart CR et al. (1977) Estimated median survival times of patients with colorectal cancer based on experience with 9.745 patients. Am J Surg 133: 289CrossRefGoogle Scholar
  70. 53.
    Spratt JS, Spjut HJ (1967) Prevalence and prognosis of individual clinical and pathologic variables associated with colorectal carcinoma. Cancer 209: 1976CrossRefGoogle Scholar
  71. 54.
    Stadler H (1985) Palliative endoskopische Lasertherapie gastrointestinaler Tumoren. Fortschr Med 20: 538Google Scholar
  72. 55.
    Steams MW, Binkley GE (1954) Palliative surgery for cancer of the rectum and colon. Cancer 7: 1016CrossRefGoogle Scholar
  73. 56.
    Sugarbaker PH, MacDonald JS, Gunderson LL (1982) Colorectal Cancer. In: De Vita VT jr, Hellmann S, Rosenberg A St (eds) Cancer Principles and practice of oncology. Lippincott, PhiladelphiaGoogle Scholar
  74. 57.
    Takaki HS, Ujiki GT, Shields TS (1977) Palliative resections in the treatment of primary colorectal cancer. Am J Surg 133: 548PubMedCrossRefGoogle Scholar
  75. 58.
    VICC (1987) In: Hermanek P, Sobin IH (eds) TNM classification of malignant tumours. Springer, Berlin Heidelbert New York TokyoGoogle Scholar
  76. 59.
    Vincent RG, Choksi IB, Takita H (1978) Surgical resection of the solitary pulmonary metastasis. In: Weiss L, Gilbert HA (eds) Pulmonary metastasis. Boston, GK Hall, p 232Google Scholar
  77. 60.
    Wagner JS, Adson MA, Van Heerden JA, Adson MH (1984) The natural history of hepatic metastases from colorectal cancer. A comparison with resective treatment. Ann Surg 199: 502PubMedCrossRefGoogle Scholar
  78. 61.
    Wanebo HE, Semoglou C, Attiyeh F, Steams MJ (1978) Surgical management of patients with primary operable colorectal cancer and synchronous liver metastases. Am J Surg 135: 81PubMedCrossRefGoogle Scholar
  79. 62.
    Wedell J, Banzhaf G, Meier zu Eissen P (1985) Neue Aspekte in der operativen Behandlung des Dickdarmileus infolge stenosierenden Coloncarcinoms. Langenbecks Arch Chir 365: 3PubMedCrossRefGoogle Scholar
  80. 63.
    Welch JP, Donaldson GA (1974) Perforative carcinoma of colon and rectum. Ann Surg 180: 734PubMedCrossRefGoogle Scholar
  81. 64.
    Welin S, Youker J, Spratt JS, et al. (1963) The rates and patterns of growth of 375 tumors of the large intestine and rectum observed serially by double contrast enema study (Malbo technique). Am J Roentgenol Rad Ther Nucl Med, 90: 673Google Scholar
  82. 65.
    Wolmark N, Fisher B, Rockette H, Redmond C (1988) Postoperative adjuvant chemotherapy or BCG for colon cancer: results from NSABP Protocol C-01. J Natl Cancer Int 80: 30CrossRefGoogle Scholar
  83. 66.
    Zakem M, Hines JD, Adelstein DJ, Rustum YM (1986) High-dose leukovorin and 5-fluorouracil in refractory and relapsed colorectal carcinoma. Proc Am Soc Clin Oncol 5: 81Google Scholar

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© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • J. M. Müller
  • W. Holzmüller

There are no affiliations available

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