Die Narkolepsien und andere Formen der Hypersomnie

  • F. Hohagen
  • E. Schönbrunn

Zusammenfassung

Obwohl sich erste Beschreibungen in der Literatur über Narkolepsie-Patienten schon im 18. Jahrhundert finden lassen (Oliver 1704), wurde das klinische Bild der Narkolepsie vor allem in der zweiten Hälfte des 19. Jahrhunderts genauer charakterisiert (Caffé 1862; Fischer 1878; Westphal 1877). In seiner Monographie „De la narcolepsie“prägte Gélineau 1880 den Namen Narkolepsie (von vaρκoσισ = Schläfrigkeit, λaμßávειv = ergreifen), worunter er ein Krankheitsbild beschrieb, das sich durch kurze imperative Einschlafattacken und „asthasias“oder plötzliche Stürze charakterisierte. Gélineau trennte die Narkolepsie differentialdiagnostisch von den Epilepsien, wobei spätere Autoren immer wieder fälschlicherweise annahmen, daß es einen Zusammenhang zwischen Epilepsie und Narkolepsie gäbe (Comelade et al. 1961; Rabending u. Schmidt 1961). Erst ein halbes Jahrhundert nach der Monographie von Gélineau wurde dann die klassische „Tetrade“beschrieben, die das Vorbild der Narkolepsie charakterisiert: imperative Einschlafattacken, Kataplexie, hypnagoge Halluzinationen und Schlaflähmung (Daniels 1934).

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Literatur

  1. Abe K (1977) Lithium prophylaxis of periodic hypersomnia. Br J Psychiatry 130: 312–313PubMedGoogle Scholar
  2. Aldrich MS (1990) Narcolepsy. N Engl J Med 323: 389–394PubMedGoogle Scholar
  3. Anderson M, Salmon MV (1977) Symptomatic cataplexy. J Neurol Neurosurg Psychiatry 40: 186–191PubMedGoogle Scholar
  4. Andreas-Zietz A, Keller E, Scholz S, Albert ED, Rotz B, Nevismalova S, Sonka K (1985) DR2-negative nacrolepsy. Lancet 11: 684–685Google Scholar
  5. Aserinski E, Kleitman N (1953) Regularly occurring periods of eye motility. Science 118: 273–274Google Scholar
  6. Association of Sleep Disorders Centers (ASDC) (1979) Diagnostic classification of sleep and arousal disorders. Sleep 2: 1–37Google Scholar
  7. Baker TL, Guilleminault C, Nino-Murcia C, Dement WC (1986) Comparative Polysomnographie study of narcolepsy and idiopathic central nervous system hypersomnia. Sleep 9: 232–242PubMedGoogle Scholar
  8. Barros-Ferreira M de Lairy GC (1976) Ambiguous sleep. In: Guilleminault C, Dement WC, Passouant P (eds) Narcolepsy. Spectrum, New YorkGoogle Scholar
  9. Billiard M (1989) The Kleine-Levin-Syndrom. In: Kryger MH, Roth T, Dement WC (eds) Principles and practice of sleep medicine. Saunders, Philadelphia, pp 377–378Google Scholar
  10. Billiard M (1981) The Kleine-Levin-Syndrom. In: Koella WP (ed) Sleep 1980. Karger, Basel, pp 124–127Google Scholar
  11. Billiard M, Seignalet J (1985) Extraordinary associations between HLA-DR2 and narcolepsy. Lancet 11: 226–227Google Scholar
  12. Billiard M, Guilleminault C, Dement WC (1975) A menstruation-linked periodic hypersomnia. Neurology 25: 436–443PubMedGoogle Scholar
  13. Billiard M, Besset A, Cadhilhac J (1983) The clinical and polygraphic development of narcolepsy. In: Guilleminault C, Lugaresi E (eds) Sleep wake disorders. Raven Press, New YorkGoogle Scholar
  14. Bonkalo A (1968) Hypersomnia. Br J Psychiatry 114: 69–75PubMedGoogle Scholar
  15. Broughton R, Mamelak M (1980) Effect of nocturnal gamma-hydroxybutyrate on sleep/waking patterns in narcolepsy-cataplexy. Can J Neurol Sci 7: 23–31PubMedGoogle Scholar
  16. Browman CP, Gujayarty KS, Sampson MG, Mitler MM (1983) REM sleep episodes during the maintanance of wakefulness test in patients with sleep apnoea syndrome and patients with narcolepsy. Sleep 6: 23–28PubMedGoogle Scholar
  17. Caffé (1862) Maladie du sommeil. J Connaiss Med Pharm 29: 323Google Scholar
  18. Carskadon MA, Dement WC (1982) The multiple sleep latenca test: What does it measure? Sleep 5: 67–72Google Scholar
  19. Carskadon MA, Dement WC, Mitler MM, Roth T, Westbrook PR, Keenan S (1986) Guidelines for the multiple sleep latency test (MSLT): A standard measure of sleepness. Sleep 9: 519–524PubMedGoogle Scholar
  20. Castaigne P, Escourolle R (1967) Etude topographique de lésions anatomiques dans les hypersomnies. Rev Neurol (Paris) 116: 547–594Google Scholar
  21. Coleman RM (1982) Periodic movements in sleep (nocturnal myoclonus) and restless syndrome. In: Guilleminault C (ed) Sleeping and waking disorders - Indications and techniques. Addison-Wesley, Menlo Park, CA, pp 265–295Google Scholar
  22. Coleman RM, Roffwarg HP, Kennedy SJ et al. (1982a) Sleep-wake disorders based on a polysomnographic diagnosis - a national cooperative study. JAMA 247: 997–1003PubMedGoogle Scholar
  23. Comelade P, Cadilhac J, Passouant P (1961) Temporal epilepsy and narcoleptic seizures. Rev Neurol (Paris) 104: 252–245Google Scholar
  24. Critchley M (1962) Periodic hypersomnia and megaphagia in adolescent males. Brain 85: 627–656PubMedGoogle Scholar
  25. Daniels L (1934) Narcolepsy. Medicine 13: 1–122Google Scholar
  26. Dement WC, Rechtschaffen A, Gulevich G (1966) The nature of the narcoleptic sleep attack. Neurology (Minneap) 16: 18–33Google Scholar
  27. Dement WC, Zarcone V, Varner et al (1972) The prevalence of narcolepsy. Sleep Res 1: 148Google Scholar
  28. Dement WC, Carskadon MA, Ley R (1973) The prevalence of nacrolepsy. Sleep Res 2: 147Google Scholar
  29. Dickel M J, Mosko SS (1990) Morbidity cut-offs for sleep-apnea and periodic movements in predicting subjective complaints in seniors. Sleen 13: 155–166Google Scholar
  30. Duffy JPF, Davison K (1968) A female case of the Kleine-Levin-Syndrome. Br J Psychiatry 114: 77–84PubMedGoogle Scholar
  31. Faull KF, Thiemann S, King RJ, Guilleminault C (1986) Monamine interaction in narcolepsy and hypersomnia. A preliminary report. Sleep 9: 246–249PubMedGoogle Scholar
  32. Fischer F (1878) Epileptoide Schlafzustânde. Arch Psychiatr Nervenkr 8: 203Google Scholar
  33. Gallinek A (1962) The Kleine-Levin Syndrome: hypersomnia, bulimia and abnormal mental states. World Nerol 3: 235–241Google Scholar
  34. Garvey M J, Mungas GD (1984) Hypersomnia in major depressive disorders. J Affective Disord 6: 283–286Google Scholar
  35. Gélineau JB (1880) De la nacrolepsie. Gaz Hop (Paris) 53:626–628, 635–637Google Scholar
  36. Guilleminault C (1976) Cataplexy. In: Guilleminault C, Dement WC, Passouant P (eds) Narcolepsy. Spectrum, New York, pp 125–143Google Scholar
  37. Guilleminault C ( 1989 a) Narcolepsy syndrome. In: Kryger MH, Roth T, Dement WC (eds) Principles and practice of sleep medicine. Saunders, Philadelphia, pp 338–346Google Scholar
  38. Guilleminault C (1989b) Idiopathic central nervous system hypersomnia. In: Kryger MH, Roth T, Dement WC (eds) Principles and practice of sleep medicine. Saunders, Philadelphia, pp 347–350Google Scholar
  39. Guilleminault C, Anders TF (1976) Sleep disorders in children. Adv Pediat 22: 155–174Google Scholar
  40. Guilleminault C, Dement WC (1977) 235 cases of excessive daytime sleepiness. J Neurol Sci 31: 13–27PubMedGoogle Scholar
  41. Guilleminault C, Grumet C (1986) HLA-DR2 in narcolepsy. Not all narcoleptic-cataplectic patients are DR2. Hum Immunol 17: 12Google Scholar
  42. Guilleminault C, Faull KF, Miles L, van den Hoed J (1983) Posttraumatic excessive daytime sleepiness: a review of 20 patients. Neurology 33: 1584–1589PubMedGoogle Scholar
  43. Hakkinen V, Fruhstorfer H (1967) Correlation between spontaneous acitvity and auditory evoked respones in the human EEG. Acta Neurol Scand 43: 106–161Google Scholar
  44. Hishikawa Y, Sumitsuji N, Matsumoto K, Kaneko Z (1965) H-reflex and EMG of the mental and hypoid muscles during sleep, with special reference to narcolepsy. Electroencephalogr Clin Neurophysiol 18: 487–492PubMedGoogle Scholar
  45. Hishikawa Y, Nan’no H, Tachibana M, Furuya E, Koida M, Kaneko Z (1968) The nature of sleep attack and other symptoms of narcolepsy. Electroencephalogr Clin Neurophysiol 24: 1–10PubMedGoogle Scholar
  46. Hobson JA, McCarley RW, Wyzinski PW (1975) Sleep cycle oscillations: Reciprocal discharge by two brain stem neuronal groups. Science 189: 55PubMedGoogle Scholar
  47. Hohagen F, Meyer G, Menche A, Riemann D, Meier-Ewert KH, Volk S, Berger M (1992) Treatment of narcolepsy-cataplexy syndrome with brofaromine, a selective and reversible MAO-A-inhibitor. (Publ. in Vorb.)Google Scholar
  48. Honda Y, Asaka A, Tanaka Y, Juji T (1983 a) Discrimination of narcoleptic patients by using genetic markers and HLA (abstract). Sleep Res 12: 254Google Scholar
  49. Honda Y, Asaka AA, Tanimura M, Furusho T ( 1983 b) A genetic study of narcolepsy and excessive daytime sleepiness in 308 families with a narcolepsy of hypersomnia proband. In: Guilleminault C, Lugaresi E (eds) Sleep/wake disorders: Natural history epidemiology and long term evolution. Raven Press, New York, pp 187–199Google Scholar
  50. Honda Y, Juji T, Matsuki K et al. (1986) HLA-DR2 and DW2 in narcolepsy and in other disorders of excessive somnolence without cataplexy. Sleep 9: 133–142PubMedGoogle Scholar
  51. Juji T, Satake M, Honda Y, Doi Y (1984) HLA-antigens in Japanese patients with narcolepsy - all the patients were DR2 positive. Tissue Antigens 24: 316–319PubMedGoogle Scholar
  52. Kales A, Bixler E, Soldatos KR, Vela-Bueno A, Caldwell AB, Cadieux RJ (1982) Biopsychobehavioral correlates of insomnia, part 1: Role of sleep apnea and nocturnal myoclonus. Psychosomatics 23: 589–596PubMedGoogle Scholar
  53. Kessler S, Guilleminault C, Dement WC (1974) A family study of 50 REM narcoleptics. Arch Neurol Scand 50: 503–512Google Scholar
  54. Kleine W (1925) Periodische Schlafsucht. Monatsschr Psychiat Neurol 57: 285–319Google Scholar
  55. Kupfer DJ, Foster FG (1978) EEG sleep and depresison. In: Williams RL, Karacan J (eds) Sleep disorders - diagnosis and treatment. Wiley, New York, pp 163–203Google Scholar
  56. Krabbe F, Magnussen G (1942) Familial narcolepsy. Acta Psychiat Neurol 17: 149–173Google Scholar
  57. Langdon N, Welch KI, Dam MC (1984) Genetic markers in narcolepsy. Lancet 11: 1178–1180Google Scholar
  58. Langdon N, Lock C, Welsh K (1986) Immune factors in narcolepsy. Sleep 9: 143–148PubMedGoogle Scholar
  59. Lavie P, Gadoth N, Gordon CR, Goldhammer G, Bechar M (1979) Sleep patterns in Kleine-Levin-Syndrome. Electroencephalogr Clin Neurophysiol 47: 369–371PubMedGoogle Scholar
  60. Levander S, Sachs S (1985) Vigilance performance and autonomic function in narcolepsy: Effects of central stimulants. Psychophysiology 22: 24–30PubMedGoogle Scholar
  61. Levin M (1929) Narcolepsy (Gelineau’s syndrome) and other varieties of morbid somnolence. Arch Neurol Psychiatry 22: 1172–1200Google Scholar
  62. Levin M (1936) Periodic somnolence and morbid hunger: a new syndrome. Brain 59: 494–504Google Scholar
  63. Lhermitte J, Dubois E (1941) Crises d’hypersomnie prolongée rhythmées par les règles chez une jeune fille. Rev Neurol 73: 608Google Scholar
  64. Lhermitte J, Hecaen J, Bineau L (1943) Un nouveau cas d’hypersomnie prolongée rhythmée par les règles. Rev Neurol 75: 299Google Scholar
  65. Lugaresi E, Cirignotta F, Coccagna G, Montagna P (1986) Nocturnal myoclonus and restless legs syndrome. Fahn S et al. (eds) Advances in neurology, vol 43: Raven Press, New York, pp 295–307Google Scholar
  66. Mamelak M, Scharf MB, Woods M (1986) Treatment of narcolepsy with gamma-hydroxybutyrate. A review of clinical and sleep laboratory findings. Sleep 9: 285–289PubMedGoogle Scholar
  67. Maxion H, Jacobi P (1970) Klinische und polyphysiographische Untersuchungen bei periodischer Schlafsucht. Dtseh Z Nervenheilkd 197: 192–202Google Scholar
  68. Meier-Ewert K, Wismans L (1984) Vigilanzleistungen bei behandelten und unbehandelten Narkoiepsiepatienten. In: Kugler J, Leutner V (Hrsg) Vigilanz, ihre Bestimmung und Beeinflussung. Hoffmann-La Roche, Grenzach-WyhlenGoogle Scholar
  69. Meier-Ewert KH (1989) Tagesschläfrigkeit: Ursachen, Differentialdiagnose, Therapie. In: Neundörfer B, Schimey K, Soyka D (Hrsg) Praktische Neurologie. Edition Medizin VCH, WeinheimGoogle Scholar
  70. Meyer JS, Sakai F, Karacan I, Derman S, Yamamoto M (1980) Sleep apnoea, narcolepsy and dreaming. Regional cerebral haemodynamics. Ann Neurol 7: 479–485PubMedGoogle Scholar
  71. Michaelis R, Hofmann R (1973) Zur Phänomenologie und Ätiopathogenese der Hypersomnien bei endogenen-phasischen Depressionen. In: Jovanovic UJ (Hrsg) The nature of sleep. Fischer, Stuttgart, pp 190–192Google Scholar
  72. Mitler MM, van den Hoed J, Carskadon MA, Richardson G, Park R, Guilleminault C, Dement WC (1979) REM sleep episodes during the multiple sleep latency test in narcoleptic patients. Electroencephalogr Clin Neurophysiol 46: 479–481PubMedGoogle Scholar
  73. Mitler MM, Gujavarty S, Browman CP (1982) Maintainance of wakefulness tests: A Polysomnographie technique for evaluating treatment efficiacy in patients with excessive somnolence. Electroencephalogr Clin Neurophysiol 53: 658–681PubMedGoogle Scholar
  74. Montplaisir J (1976) Disturbed nocturnal sleep. In: Guilleminault C, Dement WC, Pasouant P (eds) Narcolepsy. Spectrum, New York, pp 43–56Google Scholar
  75. Montplaisir J (1976) Disturbed night sleep. In: Guilleminault C, Dement WC, Passouant P (eds) Narcolepsy. Spectrum, New York, pp 43–56Google Scholar
  76. Montplaisir J, de Champlain J, Young SN (1982) Narcolepsy and idiopathic hypersomnia: Biogenic amines and related compounds in CSF. Neurology 32: 1299–1302PubMedGoogle Scholar
  77. Montplaisir J, Poirier G, Lebrun A, Decary F (1988) HLA-antigen in various forms of hypersomnia. In: Koella WP, Obal F, Schulz H, Visser P (eds) Sleep 1986. Fischer, Stuttgart, pp 407–408Google Scholar
  78. Mueller-Eckhardt G, Meier-Ewert K, Schendel DJ, Reinecker FB, Multhoff G, Mueller-Eckhardt C (1986) HLA and narcolepsy in a German population. Tissue Antigens 28: 163–169PubMedGoogle Scholar
  79. Neely SE, Rosenberg AS, Spire JP (1986) HLA antigens in narcolepsie (Abstract). Neurology 36: 299Google Scholar
  80. Nevsimalova-Bruhova S, Roth B (1972) Heredofamilial aspects of narcolepsy and hypersomnia. Arch Suisses Neurol Neurochir Psychiat 110: 45–54Google Scholar
  81. Nix WA (1990) Das Chronic-fatigue-Syndrom - Ein neues Krankheitsbild? Nervenarzt 61: 390–396PubMedGoogle Scholar
  82. Ogura C, Okuma T, Nakazawa K, Kishimoto A (1976) Treatment of periodic somnolence with lithium carbonate. Arch Neurol 33: 143PubMedGoogle Scholar
  83. Oliver W (1704) Philosophical transactions. London: 24, No. 304, 2177Google Scholar
  84. Orlosky MJ (1982) The Kleine-Levin-Syndrome: a review. Psychosomatics 23: 609–621PubMedGoogle Scholar
  85. Ott H, Bischoff RC, Oswald I et al. (1985) Review of sleep induction and hangover effects with visual analogue scales. In: Kubicki S, Herrmann WE (eds) Methods of sleep research. Fischer, Stuttgart, pp 75–91Google Scholar
  86. Pai MN (1950) Hypersomnia syndromes. Br Med J 1: 522–524PubMedGoogle Scholar
  87. Parkes JD (1985) Sleep and its disorders. Saunderes, PhiladelphiaGoogle Scholar
  88. Pohl Ö (1966) Ein Beitrag zur Pathologie der symptomatischen Narkolepsie. Dtsch Z Nervenheilkd 189: 211–217PubMedGoogle Scholar
  89. Poirier G, Montplaisier J, Decary F (1986) HLA antigens in narcolepsy and idiopathic central nervous system hypersomnolence. Sleep 9: 153–158PubMedGoogle Scholar
  90. Pressman MR, Spielman A J, Pollack CP, Weitzman ED (1982) Long latency auditory evoked responses during sleep deprivation and in narcolepsy. Sleep 5: 147–156Google Scholar
  91. Princemetal M, Bloomberg W (1935) The use of benzedrine for treatment of narcolepsy. JAMA 105: 2051–2054Google Scholar
  92. Prüll G (1963) Katamnestische Erhebungen und therapeutische Erfahrungen bei Narkolepsiekranken. Nervenarzt 34: 480–484Google Scholar
  93. Rabending G, Schmidt G (1961) Narcolepsy with subclinical spasmodic wave paroxysms in the EEG. Psychiat Neurol Med Psychol (Lpz) 13: 456–459Google Scholar
  94. Rennert H (1956) Die Narkolepsie. Monatsschr Psychiat Neurol 132: 155–172Google Scholar
  95. Reynolds CF, Coble PA, Kupfer DJ, Shaw DH (1982) Depressive patients and the sleep laboratory. In: Guilleminault C (ed) Sleeping and waking disorders — Indications and techniques. Addison-Wesley, Menlo Park/CA, pp 245–264Google Scholar
  96. Reynolds CF, Kupfer CJ, Christiansen CL, Auchenbach RC, Brenner RP, Sewitch DE, Taska LS, Coble PA (1984) Multiple sleep latency test findings in Kleine-Levin-Syndrome. J Nerv Ment Dis 172: 41–44PubMedGoogle Scholar
  97. Richardson GS, Carskadon MA, Flaag W, van den Hoed J, Dement WC, Mitler MK (1978) Excessive daytime sleepiness in man: multiple sleep latency measurement in narcoleptic and control subjects. Electroencephalogr Clin Neurophysiol 45: 621–627PubMedGoogle Scholar
  98. Riemann D, Joy D, Höchli D, Lauer C, Zulley J, Berger M (1987) Influence of the cholinergic agonist RS 86 on normal sleep. Sex and age effects. Psychiatry Res 24: 137–147Google Scholar
  99. Rosa R, Kramer M, Foright P (1979) Narcolepsy: symptom frequency in associated disorders. Sleep Res 8: 213Google Scholar
  100. Roselaar SE, Langdon N, Lock CB, Jenner P, Parkes JD (1987) Selegiline in narcolepsy. Sleep 10: 491–495PubMedGoogle Scholar
  101. Rosenkötter L, Wende S (1955) EEG-Befunde beim Kleine-Levin-Syndrom. Monatsschr Psychiat Neurol 130: 107–122Google Scholar
  102. Roth B (1957) Narcolepsy and hypersomnia from the aspect of physiology of sleep (Stätni zdravotnicke nakladatelstvi) Prague, 331Google Scholar
  103. Roth B (1962) Narkolepsie und Hypersomnie vom Standpunkt der Physiologie des Schlafes. VEB Volk u. Gesundheit, Berlin, S 428Google Scholar
  104. Roth B (1978) Narcolepsy and hypersomnia. In: Williams RL, Karacan J (eds) Sleep disorders -diagnosis and treatment. Wiley, New York, pp 29–59Google Scholar
  105. Roth B (1980) Narcolepsy and hypersomnia. Karger, BaselGoogle Scholar
  106. Roth B, Bruhova S (1969) Dreams in narcolepsy, hypersomnia and dissociated sleep disorders. Exp Med Surg 27: 187–209PubMedGoogle Scholar
  107. Roth B, Nevismalova S, Rechtschaffen A (1972) Hypersomnia with „sleep drunkeness“. Arch Gen Psychiatry 26: 456–462PubMedGoogle Scholar
  108. Roth B, Nevismalova S, Sonka K et al. (1988) A study of the occurrence of HLA DR2 in 124 narcoleptics: Clinical aspects. Arch Suiss Neurol Psychiatry 130: 41–51Google Scholar
  109. Rüther E, Meier-Ewert K, Gallitz A (1972) Zur Symptomatologie des narkoleptischen Syndroms. Nervenarzt 43: 640–643PubMedGoogle Scholar
  110. Sachs C, Persson HE, Hagenfeld K (1982) Menstruation-related periodic hypersomnia: A case study with sucessful treatment. Neurology 32: 1376–1379PubMedGoogle Scholar
  111. Sakai F, Meyer JS, Karacan I, Yamaguchi F, Yamamoto M (1979) Narcolepsy. Regional cerebral blood flow during sleep and wakefulness. Neurology 29: 61–67PubMedGoogle Scholar
  112. Schachter M, Parkes JD (1979) Deprenyl in narcolepsy. Lancet 1: 831PubMedGoogle Scholar
  113. Schafler KD (1984) Der okulodynamische Test (ODT) als Untersuchungsinstrument für pharmakologisch induzierte Vigilanzänderungen. In: Kugler J, Leutner V (Hrsg) Vigilanz. Ihre Bestimmung und Beeinflussung. Hoffmann-La Roche, BaselGoogle Scholar
  114. Schönbrunn E, Hohagen F, Berger M (1989) Hypersomnie: Klassifikation und Diagnostik. Münch Med Wochenschr 131: 579–583Google Scholar
  115. Schönbrunn E, Riemann D, Berger M (1991) Diagnose und Differentialdiagnose der idiopathischen ZNS-Hypersomnie. Aktuel Neurol 18: 100–104Google Scholar
  116. Seignalet J, Billiard M (1984) Possible associations between HLA-B7 and narcolepsy. Tissue Antigens 23: 188–189PubMedGoogle Scholar
  117. Shouse MN (1989) Epilepsy and seizures during sleep. In: Kryger MH, Roth T, Dement WC (eds) Principles and practice of sleep medicine. Saunders, Philadelphia, pp 364–376Google Scholar
  118. Sitaram N, Moore AM, Gillin JC (1978) Experimental acceleration and slowing of REM Sleep ultradian rhythm by cholinergic agonist and antagonist. Nature 274: 490PubMedGoogle Scholar
  119. Stahl SM, Layzer RB, Aminoff MJ, Townsend J J, Feldon S (1980) Continuous cataplexy in a patient with a midbrain tumor: The limp man syndrome. Neurology (NY) 30: 1115–1118Google Scholar
  120. Thal LJ, Sharpless NS (1983) Narcoelpsy and hypersomnia (letter). Neurology 33: 1394PubMedGoogle Scholar
  121. Vogel G (1960) Studies in the psychophysology of dreams III. The dream of narcolepsy. Arch Gen Psychiatry 3: 421–425PubMedGoogle Scholar
  122. Volk S, Simon O, Schulz H, Hansert E, Wilde-Frenze J (1983) The structure of wakefulness and its relationship to daytime sleep in narcoleptic patients. Electroencephalogr Clin Neurophysiol 57: 119–128Google Scholar
  123. Westphal C (1877) Eigentümliche mit Einschlafen verbundene Anfälle. Arch Psychiatr Nervenkr 7: 631–635, 681Google Scholar
  124. Wilson SAK (1928) The narcolepsies. Brain 51: 63–109Google Scholar
  125. Wolfenden WH (1969) Narcolepsy. Bull Post Grad Comm Med Univ Sidney 25: 64–68Google Scholar
  126. Yoss RE, Daly DD (1957) Criteria for the diagnosis of the narcoleptic syndrome. Proc Mayo Clin 32: 320–328Google Scholar
  127. Yoss RE, Daly DD (1960) Hereditary aspects of narcolepsy. Trans Am Neurol Assoc 85: 239–240PubMedGoogle Scholar
  128. Yoss RE, Mayer NJ, Ogle KN (1969) The pupillogram and narcolepsy. Neurology 19: 921–928PubMedGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1992

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  • F. Hohagen
  • E. Schönbrunn

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