Urease and Catalase as Virulence Factors of Helicobacter pylori

  • S. L. Hazell


Since the first report of the urease activity of Helicobacter pylori [1], this enzyme has captured a large amount of attention from researchers interested in the detection and pathogenicity of this gastric bacterium. This interest is in part aroused by the extraordinary urease activity seen in H. pylori [2–5]. Another enzyme of H. pylori noted for its vigor is catalase [6]. While not the subject of intense investigation to date, this latter enzyme may be as important to H. pylori as urease with respect to virulence and pathogenicity.


Gastric Mucosa Urease Activity Pylorus Urease Gastric Metaplasia Arginine Deiminase System 
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© Springer-Verlag Berlin Heidelberg 1991

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  • S. L. Hazell

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