Mobilization of Blood Stem Cells with Recombinant Human (rh)G-CSF in Patients with Hematological Malignancies and Solid Tumors

  • R. Haas
  • S. Hohaus
  • R. Ehrhardt
  • H. Goldschmidt
  • B. Witt
  • W. Hunstein

Abstract

Peripheral blood stem cells (PBSC) are being increasingly used for autografting in patients with malignant diseases to circumvent the myelotoxic effects of high-dose therapy [1]. It is generally accepted that the kinetics of hematological recovery following autografting essentially depend on the number of hemopoietic stem cells transplanted [2, 3]. In the past, different methods have thus been explored to improve blood stem cell collection [4, 5].

Keywords

Lymphoma Doxorubicin Cyclophosphamide Neuroblastoma Amphotericin 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • R. Haas
    • 1
  • S. Hohaus
    • 1
  • R. Ehrhardt
    • 1
  • H. Goldschmidt
    • 1
  • B. Witt
    • 1
  • W. Hunstein
    • 1
  1. 1.Department of Internal Medicine VUniversity of HeidelbergHeidelbergGermany

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