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Ventilation-Perfusion Distribution and Diffusion Limitations

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Oxygen Transport in the Critically Ill Patient

Abstract

Impaired arterial oxygenation may be caused by 1/ alveolar hypoventilation, 2/ right to left shunt, 3/ ventilation/perfusion (VA/Q) mismatch and 4/ diffusion limitation. It is obvious that reduced total Ventilation will decrease alveolar Ventilation and decrease the oxygen supply to the pulmonary capillary blood; at the same time the elimination of carbon dioxide is impeded. This cause of impaired gas exchange will not be dealt with more in this chapter. It will rather concentrate on the remaining three causes of impaired arterial oxygenation and their detection by using the multiple inert gas elimination technique [1).

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© 1990 Springer-Verlag Berlin Heidelberg

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Hedenstierna, G., Gunnarsson, L. (1990). Ventilation-Perfusion Distribution and Diffusion Limitations. In: Wendt, M., Lawin, P. (eds) Oxygen Transport in the Critically Ill Patient. Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine, vol 215. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75646-7_2

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  • DOI: https://doi.org/10.1007/978-3-642-75646-7_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52498-4

  • Online ISBN: 978-3-642-75646-7

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