Vascularization of the Peripheral Nerve in Laboratory Animals

  • M. A. Konerding
  • M. Lehmann
  • M. Blank
Conference paper


Fetterman and Spitler (1940), among others, have concluded that vascular diseases lead to ischemic neuropathies. Basing his conclusions on the first systematic studies, Adams (1942) distinguished three kinds of vessels: nutritive vessels, epineural vessels, and an intrafascicular plexus. Blunt (1959), Waksman (1961), and Lang (1962) confirmed these results.


Peripheral Nerve Sciatic Nerve Amyl Acetate Muscular Branch Endoneural Vessel 
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  1. Adams WE (1942) The blood supply of nerves. I. Historical review. J Anat 76:323–341.PubMedGoogle Scholar
  2. Blunt MJ (1959) The vascular anatomy of the median nerve in the forearm and hand. J Anat 93:15–22.PubMedGoogle Scholar
  3. Carter DC, Lee PW, Gill W, Johnston RJ (1972) The effect of cryosurgery on peripheral nerve function. J R Coll Surg (Edinb) 17:25–31.Google Scholar
  4. Dalton AJ (1955) A chrome-osmium fixative for electron microscopy. Anat Rec 121:281.Google Scholar
  5. Eames RA, Lange LS (1967) Clinical and pathological study of ischemic neuropathy. J Neurol Neurosurg Psychiat 30:215–226.PubMedCrossRefGoogle Scholar
  6. Fetterman JL, Spitler DK (1940) Vascular disorders of peripheral nerves. J Am Med Assoc 114:2275–2279.CrossRefGoogle Scholar
  7. Hiramatsu Y (1982) Stereoscopic observation of the microvasculature of peripheral nerves. Acta med. Okayama 36(4):263–275.PubMedGoogle Scholar
  8. Hodde KC, Nowell JA (1980) SEM of microcorrosion casts. Scanning Electron Microsc. II: 88–106.Google Scholar
  9. Karnovsky MJ (1965) A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron microscopy. J Cell Biol 27:137a–138a.Google Scholar
  10. Lametschwandtner A, Lametschwandtner U, Weiger T (1984) Scanning electron microscopy of vascular corrosion casts — technique and applications. Scanning Electron Microsc 11:663–695.Google Scholar
  11. Lang J (1962) Über das Bindegewebe und die Gefäße der Nerven. Z Anat Entw Gesch 123:61–79.CrossRefGoogle Scholar
  12. Lundborg G (1975) Structure and function of the intraneural microvessels as related to trauma, edema formation, and nerve function. J Bone Joint Surg 57(A):938–9PubMedGoogle Scholar
  13. Lundborg G (1979) The intrinsic vascularization of human peripheral nerves: structural and functional aspects. J Hand Surg 4:34–41.Google Scholar
  14. Lundborg G, Branemark PI (1968) Microvascular structure and function of peripheral nerves. Vital microscopic studies of the tibial nerve in the rabbit. Adv Microcir 1:66–88.Google Scholar
  15. Lundborg G, Rydevik B (1973) Effects of stretching the tibial nerve of the rabbit: a preliminary study of the intraneural circulation and the barrier function of the perineurium. J Bone Joint Surg 55(B): 390–401.Google Scholar
  16. Nobel W, Black D (1974) The microcirculation of peripheral nerves: techniques for perfusion and microangiographic, macrophotographic, and photomicrographic recordings in animals. J Neurosurg 41:83–91.PubMedCrossRefGoogle Scholar
  17. Raff MC, Asbury AK (1968) Ischemic mononeuropathy and mononeuropathy multiplex associated with diabetes mellitus. New Eng J Med 279:17–22.PubMedCrossRefGoogle Scholar
  18. Smith JW (1966) Factors influencing nerve repair. I. Blood supply of peripheral nerves. Arch Surg 93:335–341.PubMedCrossRefGoogle Scholar
  19. Stöhr M (1980) Iatrogene Nervenläsionen (iatrogenic nerve lesions). Thieme, Stuttgart New York, S 26–65.Google Scholar
  20. Waksman BH (1961) Experimental study of diphtheritic polyneuritis in the rabbit and guinea pig. III. The blood-nerve barrier in the rabbit. J Neuropathol Exp Neurol 20:35–77.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • M. A. Konerding
    • 1
  • M. Lehmann
    • 1
  • M. Blank
    • 1
  1. 1.EssenGermany

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