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Poxvirus Expression Vectors

  • Chapter
Viral Expression Vectors

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 158))

Abstract

The poxviruses form a large family of complex DNA viruses that infect both vertebrate and invertebrate hosts. The most notorious member, variola virus, was responsible for smallpox, one of the most dreaded of all infectious diseases. In the late 18th century, Edward Jenner demonstrated that smallpox could be prevented by immunization with a more benign relative, vaccinia virus, which caused mild infections in cattle. Ultimately, global vaccination strategies led to the eradication of smallpox.

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References

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Author information

Authors and Affiliations

  1. Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA

    B. Moss

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  1. B. Moss
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Editors and Affiliations

  1. Department of Microbiology School of Medicine, State University of New York at Stony Brook, Stony Brook, N.Y., 11794-8621, USA

    Nicholas Muzyczka Ph.D. (Associate Professor) (Associate Professor)

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© 1992 Springer-Verlag Berlin·Heidelberg

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Moss, B. (1992). Poxvirus Expression Vectors. In: Muzyczka, N. (eds) Viral Expression Vectors. Current Topics in Microbiology and Immunology, vol 158. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75608-5_2

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  • DOI: https://doi.org/10.1007/978-3-642-75608-5_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75610-8

  • Online ISBN: 978-3-642-75608-5

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