Orthopoxvirus Genetics

  • R. C. Condit
  • E. G. Niles
Conference paper
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 163)


The classical approach to virus genetics is limited primarily to the isolation and characterization of conditionally lethal, deletion, and drug resistant or dependent virus mutants. The ultimate goal of a genetic analysis of a virus is to provide a genetic definition of the physical map location of each gene and the biological function of each gene product. This chapter deals with the “classical” approach to genetic analysis of orthopoxviruses.


Vaccinia Virus Recombination Frequency Ribonucleotide Reductase Complementation Group Nonpermissive Temperature 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • R. C. Condit
  • E. G. Niles
    • 1
  1. 1.Department of BiochemistrySUNY/BuffaloBuffaloUSA

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