Abstract
Unusual frequency distributions of diseases involve a given diagnosis, within a given place, in a given time. However, this time-space constraint is frequently better defined for only one of these two variables. Time clusters are known as epidemics, and space clusters as endemics. Since time-space clusters are also known as epidemics, time seems to be the leading defining characteristic, probably due to the fact that the conceptual frame of epidemiology is based on infectious (communicable) diseases.
ECLAMC: Latin-American Collaborative Study of Congenital Malformations. WHO/PAHO Collaborating Centre for the Prevention of Congenital Malformations.
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Castilla, E.E., Sod, R. (1990). The Surveillance of Birth Defects in South America: II. The Search for Geographic Clusters: Endemics. In: Obe, G. (eds) Advances in Mutagenesis Research. Advances in Mutagenesis Research, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75599-6_7
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