Cell Receptors pp 495-516 | Cite as

Lineage-Specific Receptors in the Diagnosis of Malignant Lymphomas and Myelomonocytic Neoplasms

  • M. R. Parwaresch
  • H. Kreipe
  • H. J. Radzun
  • H. Griesser
Part of the Current Topics in Pathology book series (CT PATHOLOGY, volume 83)

Abstract

Surface receptors usually represent transmembrane glycoproteins serving the ability of cells to react to environmental conditions. The reaction of ligands with the corresponding receptor is the decisive event promoting transmembrane signals and triggering a complicated chain of intracellular reactions. The overwhelming majority of surface receptors in hematopoietic cells regulate growth, differentiation, defense, adaptation, and other physiological cell functions. Their involvement in neoplastic processes is mostly secondary in nature, although they may be prone to allow external influences upon the dysregulated growth mechanisms.

Keywords

Cholesterol Lymphoma Tyrosine Leukemia Corticosteroid 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • M. R. Parwaresch
  • H. Kreipe
  • H. J. Radzun
  • H. Griesser

There are no affiliations available

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