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Cytokines in Hemopoiesis, Oncology, and AIDS pp 403–409Cite as

Growth Response of Acute Myeloid Leukemic Blasts to GM-CSF In Vitro and In Vivo — Observations in One Patient

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Abstract

Treatment-induced granulocytopenia is a major dose-limiting factor for cytostatic therapy, in general, and is of high relevance in patients with acute leukemias in particular, due to the additional suppression of normal hematopoietic cells by the underlying disease. Hence, neutropenia-associated infections are the predominant cause of treatment failure, especially in elderly patients with acute myeloid leukemia (AML) undergoing intensive cytostatic therapy [1–3].

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Authors
  1. W. Hiddemann
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  2. M. Zühlsdorf
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  3. B. Wörmann
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  4. M. Koenigsmann
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  5. T. Büchner
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Editor information

Editors and Affiliations

  1. Abt. Hämatologie und Onkologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Straße 8, D-3000, Hannover 61, Germany

    Mathias Freund  & Hartmut Link  & 

  2. Abt. Pädiatrische Hämatologie und Onkologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Straße 8, D-3000, Hannover 61, Germany

    Karl Welte

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© 1990 Springer-Verlag, Berlin Heidelberg

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Hiddemann, W., Zühlsdorf, M., Wörmann, B., Koenigsmann, M., Büchner, T. (1990). Growth Response of Acute Myeloid Leukemic Blasts to GM-CSF In Vitro and In Vivo — Observations in One Patient. In: Freund, M., Link, H., Welte, K. (eds) Cytokines in Hemopoiesis, Oncology, and AIDS. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75510-1_53

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  • DOI: https://doi.org/10.1007/978-3-642-75510-1_53

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52281-2

  • Online ISBN: 978-3-642-75510-1

  • eBook Packages: Springer Book Archive

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