In Vitro Effect of Human Interferon-Gamma on Sister Chromatid Exchange Frequency and Proliferation of Cultured Human Amniotic Fluid Cells

  • R. Mertens
  • R. Flock
  • H. Habedank
  • G. Heimann


With its improved availability, interferon-gamma (IFN-γ) has become increasingly interesting for therapeutic approaches. Up to now IFN-α and ß have mainly been used in clinical trials to treat severe viral infections and certain malignant diseases. An increasing number of clinical studies is appearing concerning IFN-γ. The IFN-γ gene contains introns and has no homology with IFN-α and ß, the classical or type 1 interferons.


Amniotic Fluid Sister Chromatid Exchange Amniotic Fluid Cell Sister Chromatid Exchange Frequency Vitro Effect 
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Copyright information

© Springer-Verlag, Berlin Heidelberg 1990

Authors and Affiliations

  • R. Mertens
  • R. Flock
  • H. Habedank
  • G. Heimann

There are no affiliations available

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