New Concepts in Fluid Therapy for Patients with Intraabdominal Infection
Patients with severe intraabdominal infection develop volume requirements far beyond what would compensate for the estimated losses. These result from a massive shift of fluid and solutes from the intravascular to the interstitial compartment due to local and generalized permeability defects  and from fluid and solute losses via drainages or open packed laparostomy wounds. In addition to fluid losses from the circulation, the circulating blood volume usually is further decreased by the distributive defect associated with peripheral pooling of blood. The immediate consequences of delays in appropriate fluid therapy are inadequate organ perfusion and function.
KeywordsPermeability Albumin Dopamine Pancreatitis Gall
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- 7.Rackow EC, Falk JL, Siegel JS, Packman MI, Haupt MT, Kaufman BS, Putnam D (1983) Fluid resuscitation in circulatory shock: a comparison of the cardiorespiratory effects of albumin, hetastarch, and saline solutions in patients with hypovolemic and septic shock. Crit Care Med 11:839–850PubMedCrossRefGoogle Scholar