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A Comparative Paternity Study: DNA vs Traditional Testing

  • Conference paper
13th Congress of the International Society for Forensic Haemogenetics (Internationale Gesellschaft für forensische Hämogenetik e.V.) New Orleans, October 19–21, 1989

Part of the book series: Advances in Forensic Haemogenetics ((HAEMOGENETICS,volume 3))

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Abstract

We have analyzed 145 paternity trios using both traditional serology (six red cell systems and the HLA system), and RFLP analysis with three single-locus VNTR probes — D14S13, D2S44, and D17S79 (Lifecodes Corporation). This study was done to evaluate the benefit of using DNA testing in association with our traditional battery of tests. Specifically, we wished to (1) determine if DNA testing corroborated exclusions found by traditional testing (2) determine whether additional exclusions would be found by DNA analysis (3) evaluate the strength of the genetic evidence provided by DNA testing in cases where no exclusion was found. The results of this study indicate that DNA analysis is a very useful additional system for distinguishing non-excluded non-fathers from “true” fathers, and for providing convincing evidence in favor of paternity in cases of non-exclusion.

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References

  • Balazs I, Baird M, Clyne M, Meade E (1989) Human Population Genetic Studies of Five Hypervariable DNA Loci. Am J Hum Genet 44:182–190

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Author information

Authors and Affiliations

  1. The Blood Center of Southeastern Wisconsin Inc., Milwaukee, WI, USA

    D. J. Endean, A. M. Schmitz, C. Callaway & J. L. Gottschall

Authors
  1. D. J. Endean
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  2. A. M. Schmitz
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  3. C. Callaway
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  4. J. L. Gottschall
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Editor information

Editors and Affiliations

  1. Memorial Blood Center of Minneapolis, 2304 Park Avenue South, 55404, Minneapolis, MN, USA

    H. F. Polesky M.D

  2. Institut für Transfusionsmedizin Medizinische Fakultät, Rheinisch-Westfälischen Technischen Hochschule, Pauwelsstraße, 5100, Aachen, Germany

    Wolfgang R. Mayr

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© 1990 Springer-Verlag Berlin Heidelberg

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Endean, D.J., Schmitz, A.M., Callaway, C., Gottschall, J.L. (1990). A Comparative Paternity Study: DNA vs Traditional Testing. In: Polesky, H.F., Mayr, W.R. (eds) 13th Congress of the International Society for Forensic Haemogenetics (Internationale Gesellschaft für forensische Hämogenetik e.V.) New Orleans, October 19–21, 1989. Advances in Forensic Haemogenetics, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75496-8_23

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  • DOI: https://doi.org/10.1007/978-3-642-75496-8_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52271-3

  • Online ISBN: 978-3-642-75496-8

  • eBook Packages: Springer Book Archive

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