A Comparative Paternity Study: DNA vs Traditional Testing
We have analyzed 145 paternity trios using both traditional serology (six red cell systems and the HLA system), and RFLP analysis with three single-locus VNTR probes — D14S13, D2S44, and D17S79 (Lifecodes Corporation). This study was done to evaluate the benefit of using DNA testing in association with our traditional battery of tests. Specifically, we wished to (1) determine if DNA testing corroborated exclusions found by traditional testing (2) determine whether additional exclusions would be found by DNA analysis (3) evaluate the strength of the genetic evidence provided by DNA testing in cases where no exclusion was found. The results of this study indicate that DNA analysis is a very useful additional system for distinguishing non-excluded non-fathers from “true” fathers, and for providing convincing evidence in favor of paternity in cases of non-exclusion.
KeywordsTraditional Testing Blood Group System Standard Battery Paternity Case Alleged Father
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