A Comparative Paternity Study: DNA vs Traditional Testing

  • D. J. Endean
  • A. M. Schmitz
  • C. Callaway
  • J. L. Gottschall
Conference paper
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 3)

Abstract

We have analyzed 145 paternity trios using both traditional serology (six red cell systems and the HLA system), and RFLP analysis with three single-locus VNTR probes — D14S13, D2S44, and D17S79 (Lifecodes Corporation). This study was done to evaluate the benefit of using DNA testing in association with our traditional battery of tests. Specifically, we wished to (1) determine if DNA testing corroborated exclusions found by traditional testing (2) determine whether additional exclusions would be found by DNA analysis (3) evaluate the strength of the genetic evidence provided by DNA testing in cases where no exclusion was found. The results of this study indicate that DNA analysis is a very useful additional system for distinguishing non-excluded non-fathers from “true” fathers, and for providing convincing evidence in favor of paternity in cases of non-exclusion.

Keywords

Agarose Nylon 

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References

  1. Balazs I, Baird M, Clyne M, Meade E (1989) Human Population Genetic Studies of Five Hypervariable DNA Loci. Am J Hum Genet 44:182–190PubMedGoogle Scholar
  2. Ito H, Yasuda N, Matsumoto H (1985) The Probability of Parentage Exclusion Based on Restriction Fragment Length Polymorphisms. Jpn J Hum Genet 30:261–269Google Scholar
  3. Walker RH (ed) (1983) Inclusion Probabilities in Parentage Testing, AABB, Arlington, VirginiaGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • D. J. Endean
    • 1
  • A. M. Schmitz
    • 1
  • C. Callaway
    • 1
  • J. L. Gottschall
    • 1
  1. 1.The Blood Center of Southeastern Wisconsin Inc.MilwaukeeUSA

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